This is rather old news, but
one can imagine how Lilly ran its tests for
Humulin, in 1979-80.
There are numerous other
articles of interest where this came from
and the source is:
http:/www.oralchelation.net/data/Lillydata.htm#p1
We know that Aventis did
similar testing for Lantus' clinical trials
in 1997-8 and we know that Lilly didn't
remove Iletin I mixed beef-pork insulin from
the world market until 2 years after this
blast was published.
I thank Lauri Veneri for
directing us to it and to the list of other
interesting articles at the end of this
article. You may wish to compare it with the
October 1996 WSJ article in which ADA's Phil
Cryer complains about the over 13% of
diabetics dying from iatrogenic hypoglycemia
at:
https://members.tripod.com/diabetics_world/wsj_hypoglycemia.htm
<click here>
Maybe the
Journal was shorting Lilly Stock in '96?
(NOT likely!)
Lilly's
'Quick Cash' to Habitués Of Shelters Vanishes Quickly
By LAURIE P. COHEN
Staff
Reporter of THE WALL STREET JOURNAL
INDIANAPOLIS -- Sitting in a drab hospital room
at the Lilly Laboratory for Clinical
Research, his home for 57 days, Louis
Checchia lifts the sleeve of his navy-blue
scrubs to display a right arm that is badly
bruised and scarred from being pierced
dozens of times.
Homeless and a hard drinker, Mr. Checchia can't
say what kind of drug is being tested on
him, although he has signed an
informed-consent form. Nor has Eli Lilly
& Co.'s "Subject No. 7"
reported to the researchers any of the head
and muscle aches he has suffered in recent
weeks, as Lilly requires. He reckons
these are simply the price of quitting
drinking cold turkey to get into the study,
not the possible side effects of Lilly's
experimental drug, known only as LY315920.
The Food and Drug Administration chastised Lilly
in 1994 for using alcoholics in a drug
study.
For the 51-year-old ex-convict, any short-term
discomfort seems well worth it. When he
leaves in five days, Mr. Checchia, who has
lived on the streets of Indianapolis for the
past 14 years, will take with him $4,650 --
"in hundred-dollar bills," he
emphasizes.
Mr. Checchia is what Lilly calls a
"healthy volunteer." Each year,
some 40,000 ostensibly healthy individuals
are used by U.S. pharmaceuticals companies
to participate in so-called Phase I drug
tests. The Food and Drug Administration
requires companies to do such tests to find
out whether experimental drugs are safe
enough to give to actual patients in Phase
II testing.
Day Rates
For the pharmaceuticals industry, persuading
able-bodied people to sample untried and
potentially dangerous drugs is a tough sell.
To woo their human subjects, most companies
have to advertise heavily and shell out $125
or so a day, occasionally as much as $250;
SmithKline Beecham PLC even pays referral
bonuses. By contrast, Lilly
advertises less frequently and, at $85 a
day, pays what competitors believe is the
lowest per diem in the business.
Alone among its peers, Lilly has become
a potent magnet for homeless people. For
more than two decades, Lilly's testing
clinic has drawn from the ranks of the
homeless, often alcoholic men who drift in
and out of Indianapolis's church-run
inner-city missions. Some mission directors
privately express misgivings about this but
say they are reluctant to speak up because
they receive funding from a foundation built
on Lilly stock, even though the
foundation is independent of the company and
its clinic.
Word of mouth about testing at Lilly --
a company best known for the blockbuster
drug Prozac -- has gradually spread through
soup kitchens, prisons and shelters from
coast to coast. Today, so many homeless men
come to Indianapolis seeking admittance to
Lilly's research clinic that Matias Vega,
medical director of the local Homeless
Initiative Program, credits the clinic with
creating a "shadow economy." One
veteran nurse at the Lilly Clinic
says that the majority of its subjects are
homeless alcoholics.
'Temporarily Employed'
A Lilly official describes that notion
as "completely inaccurate." In a
written response to questions, T. Dwight
McKinney, executive director of clinical
pharmacology, says that "the vast
majority of our volunteers (roughly 94%)
have a residential address."
Earlier, in a face-to-face interview in July,
Dr. McKinney described the volunteers as
"retired or temporarily employed."
Test subjects welcome the free physical
exams and the money they get, Dr. McKinney
said, and, above all, are driven to
participate "by altruism ... . These
individuals want to help society."
But Vaughn Bryson, who was Lilly's chief
executive officer for 20 months before being
ousted in 1993, says the company's use of
homeless drinkers is "no secret."
Two homeless-shelter officials concur, as do
another former Lilly executive and
two staffers at Indiana University Medical
Center, where Lilly doctors teach.
Moreover, The Wall Street Journal
interviewed 12 men who described themselves
as homeless people who drank daily and who
said that they, and many others like them,
had participated in Lilly's Phase I tests.
Room and Board
In many ways, the practice is mutually
beneficial. For Lilly, it is
efficient and limits the risk that subjects
will sue if harmed by an experiment or
divulge particulars of a drug, say former Lilly
employees and advocates for the homeless. As
for the subjects, they get several weeks or
months of free room and board, and in
interviews they express voluble gratitude
for what they often call "easy
money."
Still, Lilly's approach raises unsettling
questions. Under FDA rules governing Phase I
trials, drugs can be tested only in people
who are able to make a "truly voluntary
and uncoerced decision" to participate.
Roger Williams, deputy director of the FDA's
Center for Drug Evaluation, contends that
using the homeless creates the very
situation the rules were designed to
prevent. He says the regulatory intent was
to discourage disadvantaged people from
participating in studies simply to escape
"the horrible situation of their daily
lives."
In addition, some public-health officials and
test experts say the use of heavy drinkers
in Phase I tests risks giving a distorted
picture of an experimental drug's safety,
which has to be ascertained before the drug
can be given to actual patients in Phase II
testing. "Alcoholism is a confounding
feature," Dr. Williams says. "When
something goes wrong, instead of saying this
is a problem with our drug, you can say this
is due to his alcoholism."
John Arnold, a pioneer of Phase I research who
founded one of the nation's first clinics
for such tests, is more outspoken. "Lilly
isn't getting the safety it needs to take
drugs into Phase II trials," he
contends. "It's for the safety of Phase
II patients that you even do Phase I."
Lilly
asserts that any prior use of alcohol by
volunteers has no significant effect on its
drug data. It says that most people who
either are undergoing alcohol withdrawal or
have liver disease severe enough to skew the
data will have abnormal physical exams and
laboratory screening tests, and thus will be
excluded.
But on the streets, Lilly's confidence in its
subjects hardly seems justified.
From the Salvation Army Mission
At 6 o'clock on a muggy Thursday morning,
Joseph LaDuke, Mark Slone and seven others
leave the Salvation Army's Harbor Light
Center, a mission where they spent the
night, trekking a little more than a mile to
the Lilly Clinic. Two days earlier,
when Messrs. LaDuke and Slone showed up at
the clinic to inquire about their prospects,
the recruiting nurse had taken down their
Social Security numbers and local residences
(a day shelter for the homeless called
Horizon House from Mr. LaDuke and an
outdated address from Mr. Slone). The nurse
then instructed them to return for a
screening.
Mr. LaDuke says he heard about Lilly's studies
from an acquaintance on the streets of
Nashville, Tenn. A cocky 23-year-old who has
been wandering the country for two years,
Mr. LaDuke says he used to be a crack addict
but now just drinks. "The only reason I
came here is to do a study so I can buy me a
car and a new pair of shoes," he says.
Mr. Slone, a soft-spoken former truck driver
who is 34, also heard of the Lilly
studies from a homeless buddy, a man in
Louisville, Ky. Mr. Slone says alcoholism
forced him into poverty. He hopes Lilly's
bounty will enable him to "get my life
back."
At 6:45, a Pinkerton security guard admits the
pair to the Lilly Clinic, housed on
the sixth and seventh floors of Wished
Memorial Hospital in downtown Indianapolis. Lilly
nurses take blood and urine samples from
about a dozen potential volunteers. Three
hours later, the screening is over. One
candidate is rejected on the spot because he
is overweight. The rest are told to return
on Monday morning at nine to be examined by
a Lilly doctor. (All but one will end
up getting into a five-week safety study of
a schizophrenia drug.)
Outside, Mr. LaDuke reports that Pattie Patrum,
the recruiting nurse, had admonished the
group to stay off alcohol for the next four
days. But Mr. LaDuke and Mr. Slone will
later recall that they wound up guzzling a
stash of Budweiser 36 hours before getting
admitted to Lilly.
No matter: Hard-drinking test subjects pride
themselves on their skill at hiding the
evidence of their binges. Regulars of Lilly
studies spend much time sampling and
swapping all manner of
"detoxifiers" they insist
guarantee entry to the clinic. Some swear by
Herbal Clean, a tea, or golden seal, an herb
grown in the Ozarks. Others say imbibing
mineral oil or vinegar does the trick. James
Picco, 57, who claims to have logged about
30 Lilly studies in 18 years but now
is too old, downed "raisins, spinach
and liver, anything with iron."
Most of those interviewed use more mundane
techniques to mask their addictions. James
Hart recalls that he would quit drinking
anywhere from three to 10 days before a
screening and fudge those dates to Lilly
staffers. "I might tell them I'd been
sober for two months when it was only three
or four days," says Mr. Hart, who
hasn't been able to get into a Lilly
study since 1994, when he was diagnosed with
hepatitis. Jerry Bienz, a 39-year-old who is
sitting outside the Lilly Clinic
waiting to be screened, confides this:
"The night before you come in, drink a
gallon or two of water 'cause that will get
your liver count down."
While elevated levels of certain liver enzymes
are, in fact, a dead giveaway for alcohol in
the system, Lilly's homeless subjects
generally manage to quit drinking long
enough to pass the blood test the clinic
gives.
A Question of Risk
Experts on the liver, where most drugs are
metabolized, are divided on whether the
tests are especially risky for heavy
drinkers. Many say no, so long as the
subjects have been off booze for a week or
more and are eating a healthy diet. But some
doctors who run Phase I tests argue that
alcoholics do face a higher risk from the
testing because they are more likely to
suffer from certain diseases that standard
blood screening doesn't detect.
"Big-time boozers may have diseases
that others don't; giving them untested
drugs could harm them," says Diane
Jorkasky, who heads SmithKline's Phase I
test site in Philadelphia.
In any case, such subjects are hardly ideal
drug-test candidates, the FDA and critics
say. The biggest problem is that homeless
alcohol abusers aren't always reliable when
it comes to reporting adverse reactions.
Sometimes they worry about being thrown out
of a study, and sometimes they confuse the
reasons for their symptoms, doctors who
conduct Phase I tests say. "If a drug
makes them dizzy or gives them a headache,
they may think it comes from detoxification
so they won't tell you, so you're
potentially skewing the safety profile of
the drug," says Philip Brown, a
physician at Pharmaceutical Research
Associates, a contract research organization
in Charlottesville, VA.
Lilly says
it continually tests and questions subjects
for side effects, and knows what to watch
for because of its preclinical data.
"Although it is impossible to be 100%
certain that every volunteer will report
every side effect, there is no reason to
believe that any characteristic of Lilly's
Phase I study population increases the
likelihood of unreported or undetermined
side effects," Dr. McKinney says.
Heavy drinkers also may metabolize a test drug
more slowly than other people do, even if
the drinkers' liver dysfunction is too mild
for the screening test to detect. Doing
safety tests on heavy drinkers thus may give
an inaccurate read of a drug's half-life,
the time it takes for it to be eliminated
from the body, essential data for figuring
out dosages. Lilly's Dr. McKinney says that
"if this had any effect, it would be
that trials of this drug would be more
cautious (i.e., slower dose escalation or
less drug exposure) in the future."
In any event, the admissions criteria at other
Phase I testing clinics are more stringent.
Other clinics don't accept smokers. They
also typically insist that subjects give a
local address and telephone number, and
recruiters often call or write to them there
before a study begins. By contrast, Lilly
drug-test subjects interviewed said it was
sufficient if they supplied the address and
phone number of a shelter or relatives. Rick
Posson, until recently the director of
Horizon House, says his shelter never
fielded any follow-up calls from Lilly
Clinic staffers. Lilly acknowledges
that it doesn't try to confirm addresses
before testing, but says that in the rare
cases where it has needed to reach a
volunteer after a study, it has been able to
do so.
Lilly is
accommodating to the homeless in other ways.
Unlike other test centers, its clinic always
houses subjects for the entire period of a
Phase I study. It is willing to store
subjects' possessions during studies.
Lilly also
now issues photo ID cards to subjects,
making it easier for them to cash checks.
The clinic says it recently began paying by
check rather than in cash, largely for
record-keeping reasons.
Elsewhere, showing up dirty and fetid will get
a volunteer booted out. Poor hygiene would
"nuke" a potential test subject at
PPD Pharmaco, a contract research
organization in Austin, Texas, says Jerry
Merritt, who oversees Phase I research. At
the Lilly Clinic, nurses simply point
slovenly test subjects to the shower, two
subjects say. A Lilly spokesman
explains, "We think it's a good idea to
offer someone a shower if they need
one."
A Lightning Rod of Controversy
The drug industry's dependence on human
subjects has long been a lightning rod for
controversy. Until the early 1960s, most
companies simply guessed at dosage levels of
new medications, and researchers would
casually distribute experimental drugs to
their physician friends to try on patients.
In 1962, after large numbers of pregnant
women in Europe were given thalidomide, a
sedative that turned out to produce birth
deformities, Congress passed new laws. These
required companies, under FDA supervision,
to test drugs on animals and healthy people
to establish maximum dosage levels for the
next phase of testing, on sick patients.
A dearth of volunteers led drug companies to
turn to the nation's prisoners, who soon
furnished virtually the entire Phase I pool.
Lilly followed suit. But by 1974, in
the wake of criticism focused on the poverty
of prisoners and the frequent promise of
early parole, the FDA required
"informed consent" from subjects
who could make a "truly voluntary and
uncoerced decision." Though the new
rules didn't specifically bar prison
research, drug companies stopped it.
By this time, finding a steady supply of
healthy people had gotten even more
difficult because the Tuskegee experiments
in Alabama, in which blacks were unwittingly
infected with syphilis, had come to light,
indelibly etching an unsavory side of human
testing into the public imagination. One
legacy of Tuskegee is that many blacks still
shun human studies, which today are
dominated by white men under 40.
Weary of the continual scramble for recruits,
most companies turned to, and continue to
rely on, university hospitals and contract
research organizations to do their Phase I
work. For reasons related to its history, Lilly
took a different route.
In 1926, Lilly became the first drug
company to operate its own clinic. J.K. Lilly
Sr., then chairman, used it to understand
more about his wife's severe anemia by
conducting tests on ailing patients,
according to an official company history.
After severing its ties to prisons in the
mid-1970s, Lilly set about expanding
this clinic to include healthy subjects,
too.
But even as others filled their Phase I studies
mostly with college-age males, Lilly
hung back. Many clinic physicians taught
part time at Indiana University's medical
school, and Lilly feared that
students would feel pressured to enlist,
says W. Leigh Thompson, who retired as
Lilly's chief scientific officer in 1995. He
says that out of similar concerns, Lilly
also barred its employees from studies.
"If you're not going to use students
and you won't use employees, you're
restricting the population," Dr.
Thompson says. (Lilly's Dr. McKinney
confirms that the company bars its employees
from participating but says it doesn't
exclude students.)
Dr. Thompson says the practice of using
homeless people was well under way when he
arrived at Lilly in 1982. "We
were constantly talking about whether we
were exploiting the homeless," he
recalls. "But there were a lot of them
who were willing to stay in the hospital for
four weeks."
He says an independent board that oversees the
clinic approved the practice. Both the board
and Lilly's top executives felt that
employing the homeless was a philanthropic
act, Dr. Thompson explains, adding that he,
too, took this position. "Providing
them with a nice warm bed and good medical
care and sending them out drug- and
alcohol-free was a positive thing to
do," Dr. Thompson says.
Lilly has
persisted in this approach despite drawing
regulatory censure following a 1993 disaster
with an experimental hepatitis drug called
FIAU. (See article below.) But as for
Lilly's overall safety record, the FDA has
no way of knowing, because oversight of
Phase I testing is limited. Robert Temple,
an official of the FDA's Center for Drug
Evaluation and Research, says: "We
haven't seen anything that makes Lilly
look worse [than other drug companies], but
we haven't looked."
Testing at the Lilly Clinic
Mr. Checchia's 57th day at the Lilly
Clinic officially begins at five in the
morning, when the lights go on in his room
and he must produce a urine sample.
Actually, Mr. Checchia says he awoke two
hours earlier and smoked a cigarette,
violating clinic rules. At 6 a.m., a nurse
takes his temperature, blood pressure and
pulse, steps that will be followed later in
the morning by an electrocardiogram and
blood draws.
He is blase about them, as well as about
"dosing days," the five separate
days in which Lilly will inject its
test drug into four male subjects aged 21 to
55. Mr. Checchia recalls that during his
last dosing experience he had to report, on
an empty stomach, to the Study Room for the
first of about 18 blood draws that day.
Then, at 10 o'clock sharp, a catheter stuck
into his arm began sending LY315920, an
experimental drug for severe infections,
through his body. (Some subjects may get a
placebo instead.) The repeated needle stabs
have created deep, discolored scars in the
crooks of Mr. Checchia's arms. But he later
boasts, "I don't feel nothing."
For Lilly's volunteers, scars are, in fact, a
macho badge. Regulars are wont to show them
off as proof of participation in multiple
studies. They also like to be stuck
repeatedly in the same place, because, they
believe, nerves in the scar tissue are
deadened, making blood draws painless.
During the long interludes between medical
sessions, subjects kill time watching TV and
playing pool in the clinic's recreation
room. Small talk centers on what they will
do with the money they get. Buying alcohol
and cars (which can double as shelter) tops
the list.
Other drug makers let Phase I subjects in
long-term studies leave their facilities
between dosings. But at Lilly,
volunteers often remain in the clinic for
weeks or months, largely to guarantee they
abstain from drinking, says Dr. Thompson,
the former chief scientific officer.
Lilly's Dr. McKinney supplies a different
rationale, explaining that the freedom to
come and go could "compromise the
safety of volunteers" in certain
studies and that an in-patient setting makes
data collection "more complete and
reliable." He says that as a result,
the study population for many trials is
limited to people who can make the time
commitment.
In any event, Lilly grants its recruits
certain perks not found elsewhere. For
example, drug companies typically bar
smokers because tobacco may change the way
the liver metabolizes drugs, and smokers are
at greater risk for certain diseases.
"You don't want them," says
SmithKline's Dr. Jorkasky.
For Lilly's volunteers, however, cigarette
breaks are a high point. Three times each
day, usually after meals, they get to leave
the clinic for a public area outside to
smoke for half an hour. Their cigarette
packs are kept by a clinic guard, and
subjects are supposed to return them to his
desk after breaks.
Mr. Checchia stows an extra pack of Pall Malls,
keeping them in the drawer of his bedside
table. Whenever he gets the urge between
official smoking breaks, he says, he sneaks
a cigarette in the bathroom. He uses a
technique volunteers favor to avoid
detection: standing on the toilet and
blowing smoke into a ceiling vent.
When cigarette supplies dwindle, volunteers
prevail on clinic nurses to buy more with
funds unwittingly provided by Lilly.
Each week, to help its subjects pass the
time, the clinic provides them with hobby
kits to make plastic car models and leather
belts and wallets. Mr. Checchia says the
kits bore him. Like many others, he sells
the kits to a guard for about $20 of
cigarette money.
Lilly says
subjects are allowed outdoor smoking breaks
if a drug protocol permits it, adding that
if a volunteer smokes, the clinic records
this, enabling it to study how cigarette
smoking affects drug metabolism. Lilly
says violations of the smoking policy can
result in dismissal from a test. It denies
that volunteers sneak smokes in the
bathroom.
Swapping War Stories
For all the apparent monotony of life in a
controlled environment, almost every Lilly
subject seems to have a war story involving
peril or pain. Whether or not they bring bad
reactions to the staff's attention, they
tell their friends.
David Pryor, a former homeless alcoholic who is
trying to establish a detox facility in
Indianapolis called Guttr Inc., describes a
120-day asthma study he was in in the late
1980s that, he says, "caused irregular
heartbeats and high blood pressure" in
four of its six participants. Mr. Checchia
says that seven years ago, an experimental Lilly
drug gave him a heart problem so bad
"they had to put things on my chest to
start my heart up again." He says the
same thing happened to another subject,
leading to their hospitalization for a short
time after the study ended. Lilly
"quit messing with that drug," Mr.
Checchia says.
More recently, Mr. LaDuke, the young man who
took part in the schizophrenia study this
summer, says the drug made him fall asleep
for two days straight. Mr. Slone chimes in
that he got excruciating headaches from it.
He says he reported the headaches.
All of the homeless test subjects interviewed
tell of slipping, after the tests, into the
shadowy recesses of urban life, gathering at
Indianapolis haunts like the Relax Inn.
Sitting behind the front desk there, manager
Doug Phillips confides that over the years
he has routinely rented rooms to guests he
refers to as "the guinea pigs."
Over the din of pinball machines, he relates
how these men typically arrive flush with
$2,500 or so in cash, staying for about a
week. "The guinea pigs go to the lounge
next door, get drunk and buy the house a
round," he says. "The idea is,
they can party for a couple of weeks and go
back to Lilly and do the next
one." Lilly requires at least 30
days between studies.
Mr. Checchia, nearing the end of his 62-day
study last June, was ready to celebrate his
first day of freedom by making a beeline for
the Dollar Inn, a $24.95-a-day motel near
the Indianapolis airport. "I'll get a
case of Miller and an escort girl and have
sex," he said. "The girl will cost
me $200 an hour."
Mr. Checchia figured his $4,650 would last
about two weeks.
Some Lilly subjects have blown through
their bankroll more quickly. Mr. Hart tells
how after a 1994 study, he left the clinic
with five other subjects, whom he had hung
out with on the streets. The group rented a
couple of rooms at the Relax Inn (then
called Chariot House). After a day-long
vodka binge, Mr. Hart fell asleep.
"When I got up, my pockets were inside
out and I was missing $1,600," says the
former Lilly Clinic regular. None of
his buddies confessed.
Boom-and-Bust Cycles
Lilly's volunteers have performed these
distinctive rites for years. But their
routines, not to mention their boom-and-bust
economic cycles, have drawn scant notice.
Some shelter directors and homeless
advocates privately attribute their silence
to their concern about the clout of the Lilly
Endowment, whose philanthropy has helped
define civic and religious life in
Indianapolis.
Established in 1937 by the Lilly family
with gifts of company stock, it now holds
16% of Lilly's shares, valued at more than
$6.5 billion, making it the company's
biggest shareholder and one of the nation's
largest charitable foundations. Lilly
officials emphasize that the company doesn't
meddle in the gift-giving decisions of the
Endowment, which has its own board. A
spokeswoman for the Endowment also says it
operates independently, adding that its
officials know nothing of the clinic's use
of homeless alcoholics.
But over the years, the Endowment has helped
every one of Indianapolis's missions for
men, and some mission staffers think of the
charity and the company as interchangeable.
Asked about Lilly's use of homeless
alcoholics, a director of one of the city's
largest missions says: "I have to be
careful with how I deal with this .Eli Lilly
has funded us and we're going to need to go
back to them this year."
At the Lighthouse Mission, director Dick Craig
says he often tries, though with scant
success, to dissuade boarders from
participating in Lilly's studies.
"These men need to deal with their
spiritual needs and emotional problems, and
they can't do that sitting in a hospital
vegging out on drug tests." But he
adds: "Eli Lilly is a big
community supporter and I'd never be
critical of the company."
The independent board charged with ensuring the
safety of Lilly's subjects also takes a
benign view. Although the board meets every
two weeks, Dr. McKinney, the clinic's chief,
says members "rarely reject"
Lilly's blueprints for drug studies. The
Rev. Harold Kallio, who was on the board for
10 years until 1994, says that if subjects
drank, "that was their own personal
life." As he puts it: "When I met
the subjects at the clinic they were sober.
On the outside, I don't know."
Late one afternoon, on an unseasonably warm
Wednesday in October, Mr. Slone and Mr.
LaDuke can once more be found sitting
outside the Harbor Light mission with their
pals.
Mr. LaDuke recounts how after he was released
from the Lilly Clinic at 2:30 p.m. on
Sept. 3, he cashed a check for $2,250 and
hit a bar. Then he went to a mall to buy the
jeans and black Nikes he now wears, as well
as a shirt he has since lost. With a fellow Lilly
subject and another homeless acquaintance in
tow, Mr. LaDuke made his way to several more
saloons, ending his odyssey at the Red
Garter, a dank topless bar. There he
polished off shots of Jack Daniels and a
cinnamon schnapps called Aftershock. Mr.
LaDuke is hazy about the details of what
happened next, except that at about 11 that
night he "blacked out."
The next morning, Mr. LaDuke says, he woke up
in the Marion County Jail "in a rubber
room with no clothes on." Gone, too,
was the rest of his Lilly loot, some
$1,700Ñwhich he believes was filched by his
drinking companions. A court clerk confirms
Mr. LaDuke's arrest for disorderly conduct
and public intoxication.
After a brief stint in jail, Mr. LaDuke managed
to reunite with Mr. Slone, who got out of
the Lilly Clinic two days later. Both
spent a few weeks in Louisville, working at
minimum-wage, temporary jobs. Now the two
are back in Indianapolis and down and out.
Determined to scare up some "quick
cash," Mr. LaDuke places a call to Ms.
Patrum, the Lilly recruiting nurse.
At the crack of dawn on Monday morning, he
strides into the Lilly Clinic to
participate in another human trial.
Copyright © 1997 Dow Jones & Company, Inc.
All Rights Reserved.
Ms.
Veneri also provided us with this
information regarding the "causes"
of diabetes:
http://www.ncirs.usyd.edu.au/facts/f-diabetes.html
This is the flip side of the debate. NCIRS
states there is no link to vaccines and
Juvenile Diabetes.
http://www.washingtonfreepress.org/61/doVaccinesMean.htm
US officials state that Dr Claussen’s
finding are irrelevant because they were
conducted on other countries population as
well
http://www.biospace.com/ccis/news_rxtarget.cfm?RXTargetID=69&SR=181
This
is interesting reading linking Diabetes to
cow’s milk fed to infants
http://www.findarticles.com/cf_dls/m0DED/1_21/65016227/p1/article.jhtml
Studies
linking the rotavirus vaccine to Diabetes
http://www.909shot.com/Diseases/juvenilediabetes.htm
This
article has some great facts linking
vaccines and diabetes and some interesting
statistics
http://www.mercola.com/article/vaccines/immune_suppression.htm
Vaccines
and Immune Suppression
http://thinktwice.com/s_rubell.htm
Rubella and its link to Diabetes
http://www.empiricaltherapies.com/Vaccination_and_Social_Violence.html
Interesting
article written by a “nonmedical” medical and medical historian, siting the
link between pertussis and diabetes along
with other vaccine related illnesses
http://www.chiroweb.com/archives/18/20/07.html
Another
article linking rotavirus and Diabetes
http://www.eurosurveillance.org/ew/1999/990506.asp
the
incidence of type 1 diabetes among children
in Finland that coincided with the
introduction of immunisation against
Haemophilus influenzae
http://www.vaccineawareness.org/vaccineflaws.htm
Explains
autoimmune disease and their link to
vaccines
http://www.parentingnaturally.net/diabetesarticles/hib.htm HIB vaccine and its link to
Diabetes
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