RABIES VACCINE BOOSTER
Patient Information/Consent Form
Rabies
Rabies is transmitted by introducing the virus into open cuts or wounds in skin or via mucous membranes. The likelihood of rabies infection varies with the nature and extent of exposure. Two categories of exposure should be considered.
Bites:
Any penetration of the skin by teeth
Non Bites:
Scratches, abrasions, open wounds, or mucous membranes contaminated with saliva or other potentially infectious material from a rabid animal.
Pre-Exposure Rabies Treatment guide with Human Diploid Cell Vaccine (HDCV)
Pre-exposure immunization should be considered for persons in high risk groups, such as veterinarians, veterinary students, animal handlers and certain travelers to foreign rabies epizootic areas.
Booster Dose
The frequent risk category includes laboratory workers, such as those doing rabies diagnostic testing, spelunkers, veterinarians and staff, animal-control and wildlife officers in areas where animal rabies is epizootic, and international travelers living or visiting (for >30 days) in areas where canine rabies is endemic. Persons among this group should have a serum sample tested for rabies antibody every 2 years and, if the titer is less than complete neutralization at a 1:5 serum dilution by Rapid Fluorescent Focus Inhibition Test (RFFIT), should have a booster dose of vaccine. Alternatively, a booster can be administered in lieu of a titer determination.
Possible Side Effects
Reactions after vaccination with HDCV are less serious and common than with previously available vaccines. In a study using five doses of HDCV, local reactions, such as pain, erythema, and swelling or itching at the injection site, were reported in about 25% of the vaccinees, and mild systemic reactions, such as headache, nausea, abdominal pain, muscle aches and dizziness, were reported in about 20% of vaccinees. An immune complex-like reaction occurs among approximately 6% of persons receiving booster doses of HDCV 2-21 days after administration of the booster dose. These patients develop generalized urticaria (hives), sometimes accompanied by arthralgia (sore point), arthritis, angioedema (swelling), erythema (redness) and nausea, vomiting fever and malaise. In no cases have the illnesses been life-threatening.
Contraindications
There are no known specific contraindications other than ongoing febrile illness. Persons who have a history of serious hypersensitivity to rabies vaccine should be revaccinated with caution.
Precautions
Since it is not known whether rabies vaccine can cause fetal harm it should be given to a pregnant woman only if clearly needed. If you have any questions, please ask now. if you experience any significant reaction, see your physician. I have read the above information about rabies and rabies vaccine and I have had a chance to ask questions. I understand the benefits and risks of rabies vaccination and request that the vaccine be given to me or the person named below for whom I am authorized to sign.
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