G l u t a t h i o n e  Utah Valley Institute of Cystic Fibrosis
NEW!  Dr. Clark Bishop, M.D., is available by email to answer your or your doctor's questions about glutathione treatment in cystic fibrosis.  He can be reached at Clark.Bishop@imail.org  NEW! Investigator's Brochure for Oral Glutathione   Everything you ever wanted to know about the clinical use of glutathione, including toxicology and safety information: click HERE Fundamental Papers  "Rethinking cystic fibrosis pathology: The critical role of abnormal reduced glutathione (GSH) transport caused by CFTR mutation," Valerie M. Hudson, Free Radical Biology and Medicine, June 2001, Vol. 30/12, pp. 1440-1461 A Layman's Explanation of GSH Augmentation Therapy for Cystic Fibrosis Patients by Valerie M. Hudson CFTR, Glutathione and Neutrophil Function," Rabin Tirouvanziam, Ph.D., Stanford University, November 1999 Related Paper by Patricia Chapman on L-Arginine and S-nitrosoglutatione (GSNO)    Reduced Glutathione in Aerosolized Form  Published Overview of Inhaled GSH Trials "The Treatment of Pulmonary Diseases and Respiratory-Related Conditions with Inhaled (Nebulized or Aerosolized) Glutathione by Jonathon Prousky, Evidence-based Complementary and Alternative Medicine, eCAM pub May 17, 2007 Preliminary Results  Clinical Trial of Buffered Inhaled GSH by Dr. Clark Bishop , published in January 2005 in Chest  Clinical Trial of Buffered Inhaled GSH by Dr. Matthias Griese, 2004 , published in 2004 in the American Journal of Respiratory and Critical Care Medicine Inhalation of GSH Plus (Buffered GSH): One Documented Case  Scientific Trial of Aerosolized Free Acid Glutathione with CF Patients (Abstract), Roum et al, 1999 Overview and Usage of Inhaled Reduced Glutathione GSH Augmentation Therapy in CF: An Initial Protocol for Interested Physicians    This is the protocol used and recommended by Dr. Clark Bishop, M.D.  Dr. Bishop  is available to answer inquiries from doctors and CF patients/parents interested in this  protocol.  He can be reached at Clark.Bishop@imail.org . General Facts About GSH Use  Rendering a  Free Acid GSH dose isotonic pH and Inhaled GSH Theranaturals' GSH Tests Free of Endotoxin Reduced Glutathione as an Oral Supplement  The Oral Supplementation of Reduced Glutathione The Role of NAC as an Oral Supplement in Concert with Reduced Glutathione Nasal Irrigation with Buffered Glutathione GSH Nasal Irrigation Information Related to Glutathione Status of CF Persons  The Role of the GSTM1 Gene Can Glutathione Help Persons With Other Diseases?  Yes!  Other Diseases Where Glutathione May be Helpful New!  Message Board for CF Persons Using Glutathione Message Board    This message board was established for CF persons using glutathione under the direction of their doctors, as a  way for people to "compare notes."    Places to Purchase Glutathione  UVICF does not recommend nor endorse using GSH without your doctor's approval and  supervision.  No member of the UVICF has any financial stake or interest in any of the  following companies, or in any company that sells glutathione. Should your doctor be interested in ordering pharmaceutical grade GSH, please refer him/her to: Buffered GSH Now Available   This is pharmaceutical grade GSH, endotoxin-free, that has been adjusted so that its pH is 5.5-6.0, and thus suitable for inhalation..  It is called GSHPlus, and is a product of Theranaturals, Inc.: their website is  http://www.theranaturals.com or email them at ,theranat@fiber.net   Oral, pharmaceutical grade free acid GSH powder encapsulated as 500 mg per capsule and called "GSH Caps" (not for inhalation!: note this company also produces buffered GSH called GSH Plus which is suitable for inhalation); Contact Theranaturals, Inc.via their website at  http://www.theranaturals.com or email them at theranat@fiber.net Oral GSH supplement capsules with added ascorbic acid (not suitable for inhalation!): Contact Health Maintenance Products concerning their Ultrathione-500 and Ultrathione-250 products at 1-800-362-8673 or  http://www.hmpscience.com GSH in sodium salt IV form, pH of 7.0 (this company is also interested in developing a pH-adjusted GSH sodium salt suitable for inhalation): Contact Professor Doctor Luigi Inderst at omnia.pharma@nvnet.it (Note: Omnia Pharmacy is located in Italy.)

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