Q: Exactly what are bio-oxidative therapies?
A: Bio-oxidative therapies involve administering small amounts of diluted ozone and hydrogen peroxide into the body for the prevention and treatment of disease. Ozone therapy has been used by licensed physicians in Germany since the early 1960's, while hydrogen peroxide therapy was developed in the United States primarily by Dr. C.H. Farr, nominee for the 1993 Nobel prize in Medicine.

Q: What is the scientific basis for bio-oxidative therapies?
A: The philosophy behind bio-oxidative therapies is a simple one. The use of hydrogen peroxide and ozone in medicine is based on the belief that the accumulation of toxins in the body is normally burnt up by the process of oxidation, a process wherein a substance is changed chemically because of the effect of oxygen on it. Oxidation breaks the toxins down into carbon dioxide and water, and eliminates them from the body. However, if the oxygen system of the body is weak or deficient (whether through lack of exercise, environmental pollution, poor diet, smoking, or improper breathing), our bodies cannot eliminate them adequately and a toxic reaction can occur. In minor cases, a toxic buildup can lead to fatigue, while a wide range of diseases can result when poor oxygenation is chronic.

Q: Are these considered "new" therapies?
A: Although few of us have ever heard of them, bio-oxidative therapies have been around for a long time. They have been used clinically by European physicians for over a century, and were first reported by Dr. T.H. Oliver in the British medical publicatio n The Lancet in 1920.1 Since that time, they have been studied in major medical research centers throughout the world, including Baylor University, Yale University, The University of California (Los Angeles) and Harvard University in the United States, as well as in medical schools and laboratories in Great Britain, Germany, Italy, Russia, Canada, Japan and Cuba. Today, between fifty and one hundred scientific articles are published each month about the chemical and biological effects of ozone and hydrogen peroxide.

Q: How do they work?
A: Bio-oxidative therapies are used to provide the body with active forms of oxygen orally, intravenously or through the skin. Once in the body, the hydrogen peroxide or ozone breaks down into various oxygen subspecies which contact anaerobic viruses and microbes [i.e. viruses and microbes which have the ability to live without air], as well as diseased or deficient tissue cells. It oxidizes these cells while leaving the healthy cells alone. When the body becomes saturated with these special forms of oxygen, it reaches a state of purity wherein disease microorganisms are killed, while the underlying toxicity is oxidized and eliminated.

According to Frank Shallenberger, M.D., who is best known in the United States for treating AIDS patients with a holistic protocol including ozone, bio-oxidative therapies have affect in the human body in the following ways:

1. They stimulate the production of white blood cells, which are necessary to fight infection.
   
2. Ozone and hydrogen peroxide are anti-virucidal.
   
3. They increase oxygen and hemoglobin disassociation, thus increasing the delivery of oxygen from the blood to the cells.
   
4. Ozone and hydrogen peroxide are anti-neoplastic, which means that they inhibit the growth of new tissues like tumors.
   
5. They oxidize and degrade petrochemicals.
   
6. They increase red blood cell membrane distensibility, thus enhancing their flexibility and effectiveness.
   
7. Bio-oxidative therapies increase the production of interferon and Tumor Necrosis Factor, which the body uses to fight infections and cancers.
   
8. They increase the efficiency of the anti-oxidant enzyme system, which scavenges excess free radicals in the body.
   
9. They accelerate the Citric Acid Cycle, which is the main cycle for the liberation of energy from sugars. This then stimulates basic metabolism. It also breaks down proteins, carbohydrates and fats to be used as energy.
   
10. Bio-oxidative therapies increase tissue oxygenation, thus bringing about patient improvement.2

Q: What exactly is hydrogen peroxide and how is it used therapeutically?
A: Hydrogen peroxide (H202) is made up of two hydrogen atoms and two oxygen atoms. A powerful oxidizer, hydrogen peroxide kills bacteria, viruses and fungi; most of us have used a 3% solution of hydrogen peroxide externally to disinfect wounds. Higher concentrations of hydrogen peroxide are used extensively in the agricultural, food and chemical industries as a disinfectant, water purifier and bleaching agent. It is also a common ingredient in contact lens cleaners, eye drops and mouthwashes.

Hydrogen peroxide is involved in all of life's vital processes, and must be present for the immune system to function properly. The cells in the body that fight infection (known as granulocytes) produce hydrogen peroxide as a first line of defense against invading organisms like parasites, viruses, bacteria and yeast. It is also required for the metabolism of protein, carbo-hydrates, fats, vitamins and minerals. As a hormonal regulator, hydrogen peroxide is necessary for the body's production of estrogen, progesterone and thyroxin; it also helps regulate blood sugar and the production of energy in cells. Hydrogen peroxide has long been used medically as a disinfectant, antiseptic and oxidizer, but has only recently been found to successfully treat a wide variety of human diseases with a minimum of harmful side effects.

The most common form of hydrogen peroxide therapy used by doctors calls for small amounts of 30% reagent grade hydrogen peroxide added to purified water and administered as an intravenous drip. However, some individuals like to add a cup of 35% food grade hydrogen peroxide to a bathtub of warm water; the hydrogen peroxide is absorbed into the body through the skin while the person soaks in the tub. Others drink a glass of water to which several drops of food or reagent grade hydrogen peroxide have been added. Although there have been reports of improved health with this method, physicians like Dr. Farr believe that taking hydrogen peroxide orally can have a corrosive effect on the stomach and small intestine and advise against using it. 3

Q: What about ozone? How is it used medically?
A: Ozone (O3) is an energized form of oxygen with extra electrons. It forms the protective ozone layer around the planet, yet becomes a pollutant when mixed with hydrocarbons (like carbon dioxide) and nitrogen oxide from automobile and factory emissions. Because scientists have focussed on the negative effects of inhaled ozone, the medicinal aspects of the gas when applied intravenously or through the skin have been largely overlooked.

Because ozone was found to be an effective bactericide and fungicide during the mid-1800's, it was first used to purify drinking water in a number of European cities. Today, over 2000 municipalities around the world- including Montreal, Paris, Los Angeles and Moscow- purify their drinking water with ozone. However, ozone was not used medically until 1915, when it was found to be an effective disinfectant of wounds and skin diseases in Germany during the First World War. It was later found that ozone has the ability to "blast" holes through the membranes of viruses, yeasts, bacteria and abnormal tissue cells and therefore killing them. Ozone was the focus of considerable research in Germany during the 1930's where it was successfully used to treat patients suffering from inflammatory bowel disorders, ulcerative colitis, Crohn's disease and chronic bacterial diarrhea. The four primary ways to administer medical ozone include:

1. Autohemotherapy, which involves removing about one half pint of blood from the patient, adding ozone and oxygen to the blood, and infusing the blood back to the patient.
2. Rectal insufflation, in which ozone and oxygen is administered as a rectal enema. The ozone/oxygen mixture is then absorbed through the large intestine.
3. Ozone "bagging", which involves having an airtight bag placed around the area to be treated. A mixture of ozone and oxygen is pumped into the bag and absorbed through the skin.
4. Ozone is also used externally in the form of ozonated olive or sunflower oil.

Q; What types of diseases can be treated with ozone and hydrogen peroxide?
A: Bio-oxidative therapies offer a tremendous range of medical application. According to the International Bio-Oxidative Medical Foundation (IBOMF), an Oklahoma-based organization devoted to research and education about these therapies, the following conditions or diseases have been treated with ozone and hydrogen peroxide with varying degrees of success:

Heart and Blood Vessel Diseases

• Peripheral vascular disease (poor circulation)
• Cerebral vascular disease (stroke and memory loss)
• Cardiovascular disease (heart disease)
• Coronary spasm (angina)
• Cardioconversion (heart stopped)
• Cardiac arrhythmias (irregular heartbeat)
• Gangrene (of fingers and toes)
• Raynaud's disease ("white finger")
• Temporal arteritis (inflammation of the temporal artery)
• Vascular and cluster headaches

Pulmonary Diseases

• Chronic obstructive pulmonary disease
• Emphysema
• Asthma
• Bronchiectasis (dilatation of bronchus or bronchi)
• Pneumocystis carinii (PCP or AIDS-related pneumonia)
• Chronic bronchitis

Infectious Diseases

• Influenza
• Herpes zoster (shingles)
• Herpes simplex (fever blister)
• Systemic chronic candidiasis (candida)
• Epstein-Barr virus (Chronic Fatigue Syndrome)
• HIV-related infections
• Acute and chronic viral infections
• Chronic unresponsive bacterial infections
• Parasitic infections

Immune Disorders

• Multiple sclerosis
• Rheumatoid arthritis
• Diabetes mellitus Type II
• Hypersensitive reactions (environmental and universal reactors)

Other Diseases

• Parkinson's Disease
• Alzheimer's Disease
• Migraine headaches
• Chronic pain syndromes (due to multiple causes)
• Pain of metastatic carcinoma
• Cancers of the blood and lymph nodes 4

Q: Is it true that ozone cures AIDS?
A: There is growing evidence that ozone (as well as hydrogen peroxide, since ozone becomes transformed into hydrogen peroxide in the body) can destroy lipid-enveloped viruses both outside and within the body, including those related to hepatitis, Epstein -Barr, cancer, herpes, cytomegalovirus and HIV. The results of a study coordinated by the Canadian Armed Forces and published in the Canadian Medical Association Journal showed that ozone kills HIV, the hepatitis and herpes viruses, and other harmful agents in the blood used for transfusion. The author of the article added, "The systemic use of ozone in the treatment of AIDS could not only reduce the virus load, but also possibly revitalize the immune system." 5 Although a related study on AIDS patients proved inconclusive, Cmdr. Michael Shannon, MD, one of the coordinators of the study, wrote that "Of interest, however, the three patients (out of ten volunteers) who responded to minor autohemotherapy in the first trial, are still alive after four years post treatment, with CD4 counts in excess of two hundred. These patients should have theoretically succumbed to AIDS within a year post-treatment."6 In several clinics in Germany, AIDS patients are being treated successfully with different types of ozone therapies, including rectal insufflation, ozone bagging, and autohemotherapy.

Bio-oxidative therapies can be an important part of holistic treatment for HIV-related problems, including lower T-cell counts, opportunistic infections, and AIDS-related diarrhea. Dan's was one such case. He was diagnosed HIV-positive and his T-cell count had dropped below 600. After only one month of ozone therapy as part of a protocol including vitamin supplements, anti-viral compounds and intestinal cleansing, his T-cell count rose to 900 and his swollen lymph nodes shrank for the first time in years.

Although there have been other cases of improvement of AIDS patients after regular ozone treatments (and several documented cases of people who were HIV+ reverting to HIV- status) ozone and hydrogen peroxide should not be considered as a "magic bullet" against HIV and AIDS. According to Frank Shallenberger, M.D. "Ozone therapy works in AIDS by acting as a an immune system modulator. In this capacity, it is very effective, safe, inexpensive and readily available. Proper therapy for AIDS will be directed at early intervention (i.e. CD4 count > 300), ozone plus other synergistic immune-augmented therapy, intestinal cleansing is paramount due to the immuno-suppressive aspect of parasites.7

Dr. Silvia Menendez, the co-founder of Cuba's Department of Ozone Department (part of the prestigious National Center for Scientific Research in Havana), suggested that ozone works best when administered as soon as possible after HIV infection, before the virus has penetrated the lymphatic system and bone marrow. The personal, economic and social ramifications of this possibility cannot be underestimated.

Q: Are these therapies safe?
A: Although ozone and hydrogen peroxide are highly toxic in their purified state, they have been found to be both safe and effective when diluted to therapeutic levels for medical use. When administered in prescribed amounts by a qualified practitioner, the chances of experiencing adverse reactions to bio-oxidative therapies are extremely small. For example, a German study on 384,775 patients evaluating the adverse side effects of over five million medically-administered ozone treatments found that the rate of adverse side effects was only 0.0007 per application. This figure is far lower than any other type of medical therapy.8

It has been estimated that over ten million people (primarily in Germany, Russia and Cuba) have been given bio-oxidative therapies over the past seventy years to treat over fifty different diseases. As cited before, they include heart and blood vessel diseases, diseases of the lungs, infectious diseases, and immune-related disorders. In some cases, bio-oxidative therapies are administered alone, while in others, they are used in addition to traditional medical procedures (such as surgery or chemotherapy) or as adjuncts to alternative health practices like megavitamin therapy, acupuncture or herbal medicine.

Q: If these therapies are so great, why aren't they used more widely in Canada and The USA?
A: Despite the fact that both ozone and hydrogen peroxide therapy have been proven in clinical trials (and in regular clinical practice) to be safe and effective in Germany, Austria, Cuba, Mexico, Italy and Russia, very few people have heard about bio-oxidative therapies in the United States and Canada. Although an estimated 15,000 European practitioners legally use bio-oxidative therapies in their practices, the number of physicians using these therapies in North America is probably fewer than 500. This is partly due to the fact that information about medical ozone and hydrogen peroxide is not provided in medical schools, and students simply do not learn about them. In addition, the medical establishment (and especially provincial and state medical boards) often discourages or prevents licensed physicians from using them in their medical practice. Some, like Dr. Robert Atkins, M.D., the author of the popular book Dr. Atkins' Diet Revolution, have been threatened with having their licenses revoked if they administer hydrogen peroxide or ozone. Clinics have been closed down and practitioners have been threatened with jail.

Q: Why is there so much prejudice against these therapies by the medical establishment?
A: A major reason for this lack of interest in bio-oxidative therapies is that ozone and hydrogen peroxide are non-patentable substances that are very inexpensive to manufacture and use. In Germany, Russia and Cuba, physicians have successfully treated many serious and chronic conditions (including cancer and heart disease) without expensive surgery. The net cost of the materials for a treatment of autohemotherapy or a medical infusion of hydrogen peroxide is under $10. Even though physicians must include professional fees and the use of their offices and equipment, bio-oxidative therapies administered in a medical setting cost up to fifty percent less than traditional therapies, especially for patients suffering from chronic and degenerative diseases. Self-administered treatments by patients themselves, while not recommended, can cost far less. For these reasons, ozone and hydrogen peroxide pose a threat to the continued dominance of the medical establishment: the pharmaceutical industry, medical centers and physicians who are accustomed to providing expensive drugs, complex medical procedures and long hospital stays.

Q: But why don't agencies like the FDA and Health and Welfare Canada encourage clinical trials on these therapies?
A: Because government health agencies are often influenced by the pharmaceutical industry and medical lobbies, objective investigation and development of effective protocols for bio-oxidative therapies have been difficult to undertake. However, the Canadian government has shown a greater willingness to investigate these therapies than American government agencies like the FDA or NIH, as shown by the HIV studies cited earlier. However, like the American press, the Canadian media largely ignored the important findings that ozone can completely remove HIV, hepatitis and herpes viruses from the blood supply.

Q: What is the future of bio-oxidative therapies?
A: After reviewing the laboratory and clinical evidence regarding the use of ozone and hydrogen peroxide, a recent report by the National Institutes of Health (NIH) on Alternative Medical Systems and Practices in the United States, has recommended that "de finitive studies be undertaken to determine whether these treatments have any utility".10 At the same time, a number of states- including New York and North Carolina- have recently passed "freedom of medicine" laws which allow the use of experimental therapies by licensed practitioners. Many physicians who are members of IBOMF from both Canada and the United States are sharing their clinical data with the goal of presenting their findings to government agencies like the NIH and FDA.

Medical ozone and hydrogen peroxide form the "cutting edge" of a new healing paradigm, involving safe, effective, natural and less costly forms of medical therapy. As more people discover the value of these therapies, there will be greater consumer demand . Because bio-oxidative therapies like hydrogen peroxide and ozone hold great promise in treating both minor health problems and some of the most devastating diseases confronting humanity today, including cardiovascular disease, cancer, and HIV-related problems at low cost, they can help solve our national health care crisis. As more physicians become acquainted with the value of these therapies, they will become a valuable part of mainstream medical practice.

Notes

1. Oliver, T.H. and Murphy, D.V., "Influenzal Pneumonia: The Intravenous Use of Hydrogen Peroxide", The Lancet, February 21, 1920, pp. 432-3.
2. Shallenberger, Frank, "Intravenous Ozone Therapy in HIV-related Disease" Proceedings: Fourth International Bio-Oxidative Medicine Conference, April 1993.
3. Farr, Charles H., letter to the author, February 4, 1994.
4. Shallenberger, Frank, letter to the author, December 9, 1993.
5. Oxidative Therapy, (Oklahoma City: IBOMF, n.d.)
6. Baggs, A.C., "Are Worry-Free Transfusions Just a Whiff of Ozone Away?" Canadian Medical Association Journal, (April 1, 1993) :1159
7. Shannon, Cmdr. Michael, letter to the author, 21 January, 1994.
8. Jacobs, Marie Theres, "Adverse Effects and Typical Complications in Ozone-Oxygen Therapy", Ozonachrichten, 1982: (1), pp. 193-201
9. Carpendale, M.T., Interview in Ozone and the Politics of Medicine (Vancouver, Threshold Film, 1993).
10. Alternative Medicine: Expanding Medical Horizons (Washington: U.S. Government Printing office, 1994)

Nathaniel Altman is the author over fifteen books on diet and health, including Oxygen Healing Therapies , which was published in April by Healing Arts Press, and distributed in Canada by Alive Books.
[ISBN: 0-89281-527-2, illustrated, 201 pp., trade paper, $12.95].

NATHANIEL ALTMAN

169 Prospect Park West Brooklyn, New York 11215 (718) 499-2384 fax (718) 499-3129

Hilda Ward, Editor
Alive! Canadian Journal of Health and Nutrition
4728 Byrne Road
Burnaby, B.C. V5J 3H7
Canada

Dear Ms. Ward:

I am the author of Oxygen Healing Therapies which was recently published by Healing Arts Press, and distributed by Alive Books in Canada. You recently published a review of the book in your magazine, for which I am very grateful. I feel that my book is the most authoritative, complete, and up-to-date book about the medical use of ozone and hydrogen peroxide (known as "bio-xidative therapies") today.

I thought that your readers may wish to learn more about these therapies, and the enclosed article offers the lay reader a clear and documented introduction on what bio-oxidative therapies are and how they work. I hope you will find it of interest. I have no problems with revising the article according to your guidelines.