In 325 BC, the Greek commander Alexander captured it. However, it was soon taken by Chandra Gupta Moriya. It remained under the rule of different rulers till Muhammad Bin Qasim defeated Raja Dahir in eighth century. Then Muslim rule over India almost lasted for a thousands years. They were replaced by Rangeet Sigh's rule in Punjab and Multan. The Sikhs were ousted by the British in 1849.

In the existing structure, Multan is renowned for being the city of saints with a rich cultural heritage and historical significance. Multan has remained a centre for spiritual education as Shah Shamas Tubraz, Bahauddin Zakariya, and Shah Rukin Alam came here and preached love, peace and humanity and they also breathed their last here.

Dupatas, chadar and suits of fascinating Multani embroidery are very popular among women. Other popular bits of Multan are clay work, both simple and with mirrors, khusas, Multani Sohan halwa and heat.

There is an old tale about Multan's famed heat. Hazrat Shah Shamas one day ordered the sun to come down and roast some meat for him. The sun came down and did what it was told. Since then Multan has had harsh summers!!!