Alcohol Dependence Children at Risk for Alcoholism The Harvard Medical School Mental Health Letter, August 1989 In a study of more than 400 Swedish boys and girls, researchers have found that the children most likely to become alcohol abusers are relatively fearless, constantly in search of novelty, and relatively indifferent to other people's opinions of them. The subjects were examined at age 11 and again at age 27. Their personalities were given a rating of one to seven on three scales: novelty seeking, harm avoidance, and reward dependence. A novelty-seeking child is curious, excitable, talkative, quick-tempered, and easily bored. A child low in harm avoidance is confident, assertive, uninhibited, and outgoing. A child with low reward dependence seems tough and emotionally cool. All of these three sets of personality traits were strongly associated with alcoholism among the boys, 30 of whom were alcohol abusers at the age of 27 (only two of the 198 girls were). Low reward dependence alone did not raise the risk of alcoholism after correlations with other personality traits were subtracted. But boys with the highest scores for novelty-seeking had more than twice the average rate of alcoholism as adults, and boys with the lowest scores for harm avoidance had three times the average rate of alcoholism. Alcoholism rates ranged from 1 percent among boys who were very low in novelty-seeking and average in harm avoidance, to 97 percent among boys who were very high in novelty-seeking and very low in harm avoidance. The risk of alcoholism also rose, although less steeply, at the other end of the scale, among boys who were very high in reward dependence (warm, sentimental, sensitive to rejection and eager for approval) or very high in harm avoidance (shy, passive, and fearful). C. Robert Cloninger, Soren Sigvardsson, and Michael Bohman. Childhood personality predicts alcohol abuse in young adults. Alcoholism, 12:494-505 (July-August 1988). © President and Fellows of Harvard College, 1989 Reprinted with permission. Internet Mental Health (www.mentalhealth.com) copyright © 1995-1997 by Phillip W. Long, M.D.