Volume 14 Number 1 WINTER, 1997
5 MINUTE EDUCATION
by Patty Geddie, RN OCN, CNS
FROM THE PHARMACY
Walt Disney Memorial Cancer Institute
Greater Orlando ONS member
Guest Contributor
ONLINE VERSION PAGE 6
5 MINUTE EDUCATION
by Patty Geddie, RN OCN, CNS
FROM THE PHARMACY
Walt Disney Memorial Cancer Institute
Greater Orlando ONS member
Guest Contributor
ABELCET (Amphotericin B Lipid Complex,
Injection)
ABELCET consists of Amiphotericin B
complexed with two phospholipids in a 1:1 drug
- to -lipid molar ratio.
Indication: for the treatment of aspergillosis in
patients who are refractory to or intolerant of
conventional Amphotericin B therapy.
Contraindications: Hypersensitivity to
Amphotericin B
Adverse Effects: chills, fever, sepsis, organ
failure, headache, infection, pain, hypotension,
nausea, vomiting, diarrhea, pancytopenia,
hypokalemia, increased serum creatinine,
dyspnea, rash, kidney failure, anaphylaxis.
Dosage and Administration: 5.0 mg/kg as a
single infusion, rate of 2.5 mg/kg/hr. If exceeds
2 hours, mix the contents by shaking the
infusion bag every 2 hours. Do not Dilute with
Saline, other drugs or electrolytes! Flush IV line
with 5% Dextrose. Do not use an inline filter
less than 5 microns!
JOURNAL CLUB
"Amphotericin B in 20% Lipid Emulsion"
This article examines administration protocols
for AmphoB Lipid Complex. Traditionally,
AmphoB has been mixed in D5W and infused
over 4 -6 hours with pre and or post hydration
and medications for side effect control. The new
form is mixed in 20% Lipid Emulsion hoping
for decreased side effects and shorter infusion
time. The author was administering the drug in
the patient's homes. In her situation, there was
no pre or post hydration, no pre-meds, and the
drug was infused over 2 hours.
AJN May 1996 Vol. 96 No. 5
"When A Loved One Is Dying: Families Talk
About Nursing Care"
The author was a co-investigator in a research
study at two major hospitals in Chicago
interviewing the next - of - kin of 30 people who
had died 3 - 5 months before. The number one
factor in family satisfaction was perceiving the
staff to having a caring attitude toward the patien
and family and to be acting on the patient's
behalf.
JOURNAL of INTRAVENOUS NURSING
May / June 1996
Number 3, Volume 19
by Kimberly A. Ryan, CRNI, BA
She did not evaluate the patient response in this
article; but referenced an article by Moreau, P.;
Milipied N.; & Fayerette N. in the Journal of
Antimicrobial Chemotherapy, 1992, that
claimed, "Reduced renal toxicity and improved
clinical tolerance of AmphoB mixed with
Intralipid compared with conventional AmphoB
in Neutropenic patients."
by Marykay Czerwiec, RN, BSN
Highest dissatisfaction was related to not being
kept informed about the patient's condition, not
being honest, and lack of this caring attitude.
Nurses had the least amount of negative
comments than any other health care team
members! The subjects noted both the nurse's
actions and attitudes. "Patient", "caring", and
"compassionate" were all used to describe the
nurses. and they were given high marks for
keeping the patient comfortable and clean.
Another important factor was just the nurse's
presence - making the family feel that she/he
would make time for them. The author gave
some suggestions for being more effective,
such as, sit down when talking with the family,
showing interest in hearing about the patient, and
actively listening. Also, don't give false hope -
families are happy just to have a nurse present.
She also suggested using the Nursing Process to
individualize how you deal with each family.
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