For the modern times Cholera appeared in the Ukraine in 1970 in Odessa and Kerch and for the last 30 years was present in the country causing some cases only. Outbreaks or isolations of Vibrio from the environment objects.

By the doctor L.Y.Mogilevsky, Ph.D (1970-2000) studying the problems of Cholera for all these years since 1970 up to 1999 in Ukraine were registered 4058 Cholera patient or vibrio cariers. Infected with Vibrio Cholera were found in all territories exsept Chmelnitskaya and Ternopolskaya regions. 3849 infected (94,8%) were found in 29 epidemic complications. During 14 outbreaks the number of infected were 10-50; in 5 outbreaks 51-100; in 4 outbreaks 101 - 200; in 5 outbreaks - 200 and more.

During the 30 years period infected with the Vibrio Cholera were found in 24 years.

The analysis of the Cholera presence in the country in the shown period gives the opportunity to mark some stages of the different intensively of the epidemic process:

1. 1970 - 1974. 1255 Cholera patients and Vibrio cariers were registrated (average No per year - 251,0), 16 administrative areas were involved in the process including Crimea and Kiev. The real epidemic dissemination of infections was marked in the separate years in Zaparizhie (1974), Donetsk (1073,1974), Odessa (1970), Kherson (1972) areas and Crimea (1970,1972,1974). In this territories 1188 (94,7%) of all registered Cholera patients and Vibrio caiers were found. At the same time in the other territories were found only 67 (5,3%) infected, majority of which came from the territories of the epidemic transmission of the disease.

2. 1975 - 1991. Only few sporadic or group cases of the disease or the cariers status were registered. Total - 85 cases of Cholera or cariers (average No per year - 5,3).

78 from the territories where in 1970-1974 the epidemic form of infection was registered.

3. 1991 - 1995. The periods of the epidemic period increase. 2679 Vibrio Cholera infected were registered (average No per year - 535,8).

Two new areas Dnepropetrovskaya and Donetskaya regions gathered to the group where the epidemic form of infection was registered in 1970-1974. (Zaporozhie, Donetskaya, Odessakaya, Khersonskaya, AR Crime). 67,2% of infected in this period and 44,4% of all the carriers in the Ukraine during the 7^th pandemic were registered in Nikolaev Area.

66 cases were found in 10 other regions as the transmission from the epidemic registration territories.

After the 1994-1995 outbreak there were fixed only a few cases of the disease and carier status. Only 39 infected were found in 1996-1999. All infected were found in the territories with the epidemic development in past, except one case.

All this shows the decrease of the Cholera Epidemic process in the Ukraine and the start of the new stage.

The correlative analysis of the 7Pandemic Cholera epidemic process in the Ukraine and the world indicates the clear synchronization of the increase and decrease stages.

Tabl.1. Cholera in the world and the Ukraine during the 7^th Pandemic.

Territory Average per year No of the Cholera cases.

Ukraine

World

This synchronization shows the same tendencies in the Cholera 7^th pandemic development in the world and the Ukraine and the presence of the Epidemic situations in the Ukraine in the years and the cases of the first registration in the border Countries (Russia, Romania, Moldavia) or distant (Turkey) which shows the transmisive model of the outbreaks of the infection in the country.

The long term investigations (1970-2000) of the 7^th Cholera Pandemic specifies in the Ukraine demonstrated the epidemic model development in the cities, towns or villages located in the Southern Part of the Ukraine in 6 areas (Donetsk, Dnepropetrovsk, Zaporogie, Nikolaev, Odessa, Kherson) regions and AR Crimea. The majority of the Cities were on the banks of the open water, which was the end point for the non-treated wastewater. At the same time these water are using for the recreation and other needs of population.

It is clear the attesting mechanism for the epidemic process in the involved areas is the contact of the population with the Vibrio Cholera polluted wastewater.

All mentioned about showed the same problems in the 7^th Cholera Pandemic for the Ukraine as for the whole world. It is extremely important to study factors of the transmission and the mechanisms of the epidemic and outbreaks. For the practice we need to create the guaranteed system of water use, canalization, wastewater treatment and the protection of the environment for the infection pollution.

For the specific medical problems development we need to use the modern laboratory technologies able to recognize the diseases in materials from environment and Sick. These adequate technologies are important to obtain the comparable results to share and compare the data from the different countries including the Ukraine.

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