1. Bobby Charlton      754   1956-73
 2. Bill Foulkes        682   1952-70
 3. Alex Stepney        535   1966-78
 4. Tony Dunne          530   1960-73
 5. Joe Spence          510   1919-33
 6. Arthur Albiston     482   1974-88
 7. Brian McClair       467   1987-98
 8. George Best         466   1963-74
 9. Mark Hughes         460   1983-95
10. Bryan Robson        456   1981-94
11. Martin Buchan       455   1972-83
12. John Silcock        449   1919-34
13. Gary Pallister      431   1989-98
14. Jack Rowley         422   1935-55
15. Sammy McIlroy       418   1971-82
16. Steve Bruce         409   1987-96
17. Lou Macari          400   1972-84
18. Denis Law           399   1962-73
19. Steve Coppell       395   1974-83
20. Paddy Crerand       392   1962-71
 =  Nobby Stiles        392   1960-71
22. Allenby Chilton     390   1939-55
23. Mike Duxbury        376   1980-90
24. Gary Bailey         373   1978-86
25. Denis Irwin         371   1989-
26. Shay Brennan        355   1957-70
27. Stan Pearson        345   1937-54
28. Johnny Carey        344   1937-53
29. David Sadler        333   1963-74
30. Billy Meredith      332   1906-21

At the start of the 1998-99 season, Ryan Giggs had played 311 games.