| Week | Date | Lecture/Recitation |
| 1 | March 28th | Course Overview
Overview of nucleic acid and protein structure and organization |
| 2 | April 4th | Information theory and the informational content of biomolecules (nucleic acids, proteins and polysaccharides)
Major databases relevant to the primary sequences of DNA, RNA, proteins and polysaccharides {CH1, CH2, CH5} |
| 3 | April 11th | Computer-aided analyses of genomic DNA: control elements, intron/exon assignments, etc.
Principles of global and local primary sequence alignments {CH7, CH8, CH10} |
| 4 | April 18th | Continuation of Lecture #3 (Dynamic Programming for sequence alignments)
Program suites for computer-aided recombinant DNA research, e.g., the Genetics Computer Group (GCG) {CH4} |
| 5 | April 25th | Genomics: an emerging resource for determining evolutionary relationships {CH13}
Special Projects List (Handout) |
| 6 | May 2nd | Consensus protein motif sequences: the structure and application of Prosite and related databases {CH8}
Secondary and higher order protein structure databases {CH11} |
| 7 | May 9th | Proteome Informatics: Approaches and applications of genome-encoded proteins
Protein Data Bank (PDB): the organization of PDB files for analyzing 3-dimensional biomolecular structures {CH13} |
| 8 | May 16th | Molecular model visualization and molecular "modeling-by-homology"-I {CH8, CH11}
Molecular "modeling-by-homology"-II |
| 9 | May 23rd | Bioengineering proteins by molecular "modeling-by-homology"
Student Recitations: Special Projects |
| 10 | May 30th | Student Recitations: Special Projects |
| 11 | June 6th | Final Exam |