| This is an actual series of BG
                readings performed by one of our members
                (Dr. Brent Hoadley) with various insulins
                and even pump therapy trying to build a
                reasonable level of control for his
                diabetes.  The only practicable insulin
                choices he found were beef R and beef-pork
                UL (no beef UL was available at the time and
                no pork UL is available either, some of us
                have had success with beef PZI). 
                Carbohydrate intake was Null on the basal
                tests with 15gms CHO at hour 3 and 15gms CHO
                at hour 4 on the bolus tests.  These
                rigorous tests were performed to quantify
                and evaluate the available insulins as he
                attempted build reasonable control of his
                diabetes.  Dr. Hoadley had developed
                severe retinopathy within 16 years of his
                diagnosis (1954) which occurred when he was
                14 years old and has other microvascular
                complications in spite of he efforts to find
                and maintain good glycemic control. 
                The target for these tests was to maintain
                BG between 80mg/dl (4.44mM/L) and 180mg/dl
                (9.99mM/L).   Only beef insulins
                allowed this with the exception of the
                initial CIIT Humalog® therapy, but within 2
                months, it had become unreliable and life
                threatening.  These tests display the
                need for beef insulins without regard to the
                hypoglycemia [insulin
                reaction/insulin shock- ed]
                unawareness problem which Dr. Hoadley also
                experienced on Humulin® rDNA human,
                Humalog® rDNA analogue synthetic, and
                Iletin® 2 monocomponent porcine insulins. 
                    Brent's
                    Basal: (click to view Bolus) |