This is an actual series of BG
readings performed by one of our members
(Dr. Brent Hoadley) with various insulins
and even pump therapy trying to build a
reasonable level of control for his
diabetes. The only practicable insulin
choices he found were beef R and beef-pork
UL (no beef UL was available at the time and
no pork UL is available either, some of us
have had success with beef PZI).
Carbohydrate intake was Null on the basal
tests with 15gms CHO at hour 3 and 15gms CHO
at hour 4 on the bolus tests. These
rigorous tests were performed to quantify
and evaluate the available insulins as he
attempted build reasonable control of his
diabetes. Dr. Hoadley had developed
severe retinopathy within 16 years of his
diagnosis (1954) which occurred when he was
14 years old and has other microvascular
complications in spite of he efforts to find
and maintain good glycemic control.
The target for these tests was to maintain
BG between 80mg/dl (4.44mM/L) and 180mg/dl
(9.99mM/L). Only beef insulins
allowed this with the exception of the
initial CIIT Humalog® therapy, but within 2
months, it had become unreliable and life
threatening. These tests display the
need for beef insulins without regard to the
hypoglycemia [insulin
reaction/insulin shock- ed]
unawareness problem which Dr. Hoadley also
experienced on Humulin® rDNA human,
Humalog® rDNA analogue synthetic, and
Iletin® 2 monocomponent porcine insulins.
Brent's
Basal: (click to view Bolus)
|