Progesterone in Pregnancy

When

Normal Values

What Level Means

Mid-Luteal Phase

5+ ng/ml

As mentioned above, a level of 5 indicates some kind of ovulatory activity, though most doctors want to see a level over 10 on unmedicated cycles, and over 15 with medications. There is no mid-luteal level that predicts pregnancy.

First Trimester

10-90 ng/ml

Average is about 20 at 4 weeks LMP, and 40 at 14 weeks LMP. It is important to note that while a higher progesterone level corresponds with higher pregnancy success rates, one cannot fully predict outcome based on progesterone levels. Progesterone supplementation is unlikely to help if started after a positive pregnancy test.

Second Trimester

25-90 ng/ml

Average is 40 at beginning, 90 at end.

Third Trimester

49-423 ng/ml

Usually peaks at about 175.