The Daughters are distinctly modern phenomena despite their Classical name. No Kindred claims to have heard of them before the 1700s, and if they had existed, vampires feel sure they would have known. The Daughters are such masters of song that most Kindred believe they are an offshoot of the Toreador, though those who have been on the receiving end of their powers think the Malkavians had more influence.
The Daughters of Cacophony are singers without peer, but their melodious harmonies are not their main claims to fame. It is the damage their songs can do to the mind that causes their Kindred concern. The Toreador are of two minds in their dealings with this bloodline. While they cannot deny that the Daughters have in credible skill in their chosen art, more than one Toreador has been forever twisted by one disjointed note. The Daughters’ songs can be as horrid as they can be beautiful, and there is no way to know their intentions until they act.
The Daughters are a small bloodline, centered mainly in the New World, and members Embrace only those who show real singing talent. Most create no more than one or two childer. The childer learn from their sires for years before being released into the world. The Daughters go to great lengths to avoid Embracing anyone of wide renown, but most of the line’s members were beginning promising careers in music at the time of the Embrace. They retain their love of performance, but perform mainly for each other and for their small Herds. They keep their Fame minimal, but often find the lure of small clubs too much to ignore. Hearing such a performance can be an unmatched experience for anyone.

Appearance: There is no standard look to this bloodline. Its members have included beefy opera singers, pencil-thin divas and everything in between. While some of its most prominent members have been female, the bloodline includes a fair number of males, though most are rather young.

Haven: Trendy apartments, lofts and nightclubs seem to be their residences of choice.

Background: Any one Embraced into this bloodline will have a beautiful voice, but does not have to be a professional musician. Still, most were.

Character Creation: Daughters of Cacophony almost always have entertainer concepts. They split their most popular Natures between Visionary and Praise-Seeker, though they may take any Demeanor. Social Attributes and Talent Abilities are almost always primary. They always have at least some Fame, but can have any other Backgrounds they desire. Most will also have Herds for whom they perform. Many have developed the Baby Face Merit. While they seem to abide by the Masquerade, Daughters can be found in both the Camarilla and the Sabbat.
Some Kindred insist the Daughters have undying loyalty to whatever sect rules the city in which they reside. For instance, one famous Daughter, Sayshila, is known to have stopped a Sabbat attack on a Miami concert house. On the other hand, she is believed to have driven a Gangrel archon mad after the pair spent a night together howling at the moon.

Nickname: Sirens 

Disciplines: Fortitude, Melpominee, Presence

Weaknesses: 

Organization: The bloodline has no formal organization, but younger members generally follow the lead of the older, more talented members. Occasionally a number of Daughters gather to give a concert of great beauty.

Gaining Bloodline Status: The easiest way to gain Prestige among the Daughters is through musical ability. Some rumors speculate that Daughters also gain Prestige based on the number of Kindred and kine their music has driven crazy.

Quote: “Aaaaaaaaaaaaaaaaaahhhhhhhhhhhhhhhh," (crash, as the glass breaks)

Updated section from Guide to Camarilla

It is only in the modern nights that the Daughters of Cacophony have truly eamed their name, culling the men, castrati and boys from their ranks for reasons unknown. The remaining Daughters have no inclination to talk about the topic, and instead seem to be wholly enthralled by the process of creating and performing music. Politics and warfare, it seems, mean nothing to these Kindred. Only music, of all the arts, holds any attraction for them at all.
Camarilla Daughters seem to belong to the sect out of convenience, not conviction. If a city is Camarilla, then the local Daughters abide by Camarilla laws and Traditions without so much as a mellifluous grumble. Daughters of Cacophony have no great love for the sect, but no great dislike of it either, and it has been noted that the bloodline tends to follow the Masquerade whether it is enforced locally or not. There is also speculation that the Daughters prefer dealing with the Camarilla clans to dealing with the Tzimisce and Lasombra of the Sabbat, but speculation is all it is. In the meantime, the Kindred of the Camarilla generally agree that it’s better to have the Daughters on the inside than the outside, and best of all to have them so completely distracted by their projects that they pay the rest of the world no heed at all.

Dealing With Others: The Camarilla offers an abundance of clans with whose members the Daughters delight in dealing so to speak. The Ventrue offer patronage, the Malkavians inspiration and the Toreador collaboration, companionship and competition. Among those three clans, there’s more than enough to keep a Daughter busy at Elysium. The other clans of the Camarilla don’t seem to interest the Daughters precious little does, after all but at least there seems to be no active hostility present, either. A Daughter of Cacophony does not recoil in honor from a Nosferatu; she just has nothing to say to him.
Sirens (for so the bloodline is nicknamed) never take positions in a city’s government. A few have been known to deign to sit with the harpies on occasion, but a Daughter serving as primogen, sheriff or deo prohibe prince is a notion beyond the bounds of possibility. Those Daughters who are in the Camarilla have no interest in shaping it or its policies.

Roleplaying: Daughters of Cacophony are devoted, at least in public, to their art. Whatever the bloodline’s hidden agenda might be, individual Daughters’ behavior in public always follows the same pattern: devotion to singing and music, a complete apathy toward all things political, and utter disdain for any not so talented as they. Despite their disinterest in all things martial, the Daughters do not hesitate to defend themselves (and some say that the threshold of provocation has been reduced as the bloodline’s songs have grown in power) with all the force at their disposal.
On the other hand, Sirens are often inclined to look favorably on those who praise their work intelligently “You sing real purty” isn’t likely to win a Daughter’s favor. The Daughters are also likely to haunt local Elysiums in search of powerful and educated patrons. What the Daughters do with those patrons is a mystery best left to the darkest recesses of the imagination at least if you believe the rumors.