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Cristina: You are eight feet tall. Your boobs are perfect. Your hair is down to there. If I was you I would just walk around naked all the time. I wouldn't have a job, I wouldn't have any skills, I wouldn't even know how to read. I would just be... naked.
Izzie: It's makeup. It's retouching.
Cristina: You get that we hate you, right?*

Izzie: [to Alex] You wanna see it? You really wanna see it? Fine! Let's look at that tattoo up close and personal, shall we? [she rips off her shirt]: What are these? Oh, my God! Breasts! How does anybody practice medicine hauling these things around? And what have we got back here? Lets see if I remember my anatomy. [takes off her pants] Gluts, right? Lets study them, shall we? Gather around and check out the booty that put Izzie Stevens through Med. school! You wanna call me Dr. Model? That's fine. Just remember that while you're still sitting on two hundred grand of student loans, I'm out of debt.*

George: This shift is a marathon, not a sprint. Eat.
Izzie: I can't.
George: You should eat something.
Izzie: You try eating after performing 17 rectal exams. The Nazi hates me.
George: The Nazi's a resident. I have attendings hating me.*

Bailey: You wanna tell me what that was all about?
Izzie: Nothing. He's probably just crazy or something. [she hesitates] Bethany Whisper.
Bailey: What?
Izzie: Bethany Whisper. I did a new Bethany Whisper lingerie ad, he saw it in a magazine.
Bailey: You had time to pose for magazines?
Izzie: No, it was last year, it just came out.
Bailey: So, because he saw you in a thong--
Izzie: No! It was not a thong!
Bailey: You're hiding out in the hallway?
Izzie: I think it might be easier if you assign another intern.
Bailey: Izzie, it's not in your job description. You are a doctor. He is a patient. He's your patient! Biopsy these! If they come back positive, I expect to see you in surgery. You're on this! You hear me?*

Dr. Saltzman (Therapist): What do you need to make this marriage work?
Derek: I need her to move to Seattle.
Addison: That’s just--
Dr. Saltzman: Addison, what do you need?
Addison: I need him to stop talking to Meredith.
Derek: I work with her.
Addison: You want me to pick up my entire practice and move here, fine. I want you to give up your girlfriend.
Derek: I did give up my girlfriend. Okay, you wanted me to take you back. I took you back here in Seattle.
Addison: See, once again it’s all about what he wants.
Derek: Okay, she’s not listening to me. I’m not gonna move back to Manhattan. I’m not the same person you’re used to.
Addison: I know you’re a flannel wearing, wood chopping fisherman. I get it.
Derek: Oh that’s just great.  I’m not gonna talk to her anymore if she’s gonna behave like this.
A timer goes off.
Addison: Fine.
Dr. Saltzman: Sorry guys. Times up. Good progress.
Derek and Addison stare at him in total disbelief.

Meredith: I am an evil mistress.
George: But still... you look nice.*

Addison: [in Dr. Saltzman’s office] I’ve given it a lot of consideration and I’ve decided to move to Seattle.
Derek: And…well, Meredith won’t be an issue anymore. She’s out of my life. It’s well… It’s taken care of.
Dr. Saltzman: Well, I must say this is ah remarkable progress. I applaud both of you. You’ve taken a very significant leap.
Addison: That’s what marriage is about. Compromise, right?
She reaches out to take Derek’s hand but he just stares at her hand.
Derek: Yeah. It’s… Well, it’s about… Well, give and take.
Derek stretches his hand toward Addison but she’s withdrawn her hand.

Addison: Derek, are you done? Hurting me back, I mean. Because I need to know because if not I need to special order a thicker skin or something.

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Source Photographs from ABC.com

*Quotes from IMDb