Calcium-binding Proteins
2. The isolation and characterization of calmodulin-binding proteins and investigation of how these targets interact with calmodulin. Although more than 70 calmodulin-binding proteins are known, less than half of these proteins are characterized. Calmodulin is a ubiquitous calcium-binding protein which is critical for many cellular processes including memory and growth. Understanding the mechanism by which intracellular calmodulin is regulated is vital to the overall understanding of the second messenger function of calcium.
Gomes AV, Barnes JA, Vogel HJ. (2000) Spectroscopic characterization of the interaction between calmodulin-dependent protein kinase I and calmodulin. Arch Biochem Biophys. 379,28-36.
Barnes, J.A. and Gomes, A.V. (1995) PEST sequences in calmodulin-binding proteins. Molecular and Cellular Biochemistry, 149/150, 17-27.
Related links
- Calmodulin
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- Calcium-binding Database
- - Basic information on more than 30 EF-hand Ca2+-binding proteins
- Prof. H. J. Vogel (University of Calgary)
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- Prof. B. Sykes (University of Alberta)
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- Prof. J.D. Potter (University of Miami)
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Pictured from left-right, front row, James Potter, Rosalyn Lang, Michelle Jones, Todd Miller; middle row, Zoraida Diaz-Perez, Debalina Ghosh, Danuta Szczesna, Georgiana Guzman, Jiaju Zhao; back row, Fatima deFreitas, Aldrin Gomes.
The Mexican Yam Bean
3. The promotion of the Mexican Yam Bean (Pachyrhizus erosus L. Urban) as a potential West Indian crop of economic importance. This genus Pachyrhizus is attributed with the highest production of leguminous tubers on a world basis. On a dry weight basis, the Mexican Yam Bean contains 2-4 times the protein content of other tubers such as yam and cassava.
Barnes, J.A. and Gomes, A.V. (1998) The Yam Bean: a plant of promise. Biologist 45, 221-224.
Gomes, A.V., Sirju-Charran, G. and Barnes, J.A. (1997) Major proteins of Yam Bean tubers. Phytochemistry 46,185-193.
Related links
- Basic information about Yam Bean
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Protein Gel Electrophoresis
4. Improvements in Protein Gel Electrophoresis (PAGE) Methods.
Gomes, A.V. and Barnes, J.A. (1998) Cost- and time-efficient gel electrophoresis for mini-gel systems. Anal. Biochem. 260,106-108.
Related links
- Protein gel electrophoresis troubleshooting guide
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- Back to my Homepage
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