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Full Scientific Publications
Klonizakis M, Bianchi SM, Gernigon M, Abraham P, Nawaz S. Real-life adaptations in walking patterns in patients with established
peripheral arterial disease assessed using a global positioning system in the community: a cohort study. Clin Physiol Funct
Imaging. 2018 Jan 24. doi: 10.1111/cpf.12501
Mitropoulos A, Gumber A, Crank H, Klonizakis M. Validation of an Arm Crank Ergometer Test for Use in Sedentary Adults. J
Sports Sci Med. 2017 Dec 1;16(4):558-564.
Tew GA, Gumber A, McIntosh E, Kesterton S, King B, Michaels JA, Klonizakis M. Effects of supervised exercise training on
lower-limb cutaneous microvascular reactivity in adults with venous ulcers. Eur J Appl Physiol. 2018 Feb;118(2):321-329. doi:
10.1007/s00421-017-3772-0.
Klonizakis M, Tew GA, Gumber A, Crank H, King B, Middleton G, Michaels JA. Supervised exercise training as an adjunct therapy
for venous leg ulcers: a randomised controlled feasibility trial. Br J Dermatol. 2017 Oct 27. doi: 10.1111/bjd.16089.
Oggioni C, Jakovljevic DG, Klonizakis M, Ashor AW, Ruddock A, Ranchordas M, Williams E, Siervo M. Dietary nitrate does not
modify blood pressure and cardiac output at rest and during exercise in older adults: a randomised cross-over study. Int J
Food Sci Nutr. 2018 Feb;69(1):74-83. doi: 10.1080/09637486.2017.1328666.
Klonizakis M, Crank H, Gumber A, Brose LS. Smokers making a quit attempt using e-cigarettes with or without nicotine or prescription
nicotine replacement therapy: Impact on cardiovascular function (ISME-NRT) - a study protocol.BMC Public Health. 2017 Apr
4;17(1):293. doi: 10.1186/s12889-017-4206-y.
Hodges GJ, Mallette MM, Tew GA, Saxton JM, Moss J, Ruddock AD, Klonizakis M. Effect of age on cutaneous vasomotor responses
during local skin heating. Microvasc Res. 2017 Jul;112:47-52. doi: 10.1016/j.mvr.2017.03.002.
Siervo M, Oggioni C, Jakovljevic DG, Trenell M, Mathers JC, Houghton D, Celis-Morales C, Ashor AW, Ruddock A, Ranchordas
M, Klonizakis M, Williams EA. Dietary nitrate does not affect physical activity or outcomes in healthy older adults in a randomized,
cross-over trial. Nutr Res. 2016 Dec;36(12):1361-1369. doi: 10.1016/j.nutres.2016.11.004.
Lenasi H, Klonizakis M. Assessing the evidence: Exploring the effects of exercise on diabetic microcirculation. Clin Hemorheol
Microcirc. 2016;64(4):663-678.
Wasilewski R, Ubara EO, Klonizakis M. Assessing the effects of a short-term green tea intervention in skin microvascular
and oxygen tension in older and younger adults. Microvasc Res. 2016 Sep;107:65-71. pii: S0026-2862(16)30048-6.
Tew GA, Michaels J, Crank H, Middleton G, Gumber A, Klonizakis M. Supervised exercise training as an adjunctive therapy for
venous leg ulcers: study protocol for a randomised controlled trial. Trials. 2015 Oct 6;16(1):443. doi: 10.1186/s13063-015-0963-z.
Middleton G, Keegan R, Smith MF, Alkhatib A,Klonizakis M. Brief Report: Implementing a Mediterranean Diet Intervention into
a RCT: Lessons Learned from a Non-Mediterranean Based Country. J Nutr Health Aging. 2015;19(10):1019-22.
Klonizakis M, Manning G, Lingam K, Donnelly R, Yeung JM. Effect of diabetes on the cutaneous microcirculation of the feet
in patients with intermittent claudication. Clin Hemorheol Microcirc. 2015;61(3):439-44.
Humeau-Heurtier A, Klonizakis M. Processing of laser Doppler flowmetry signals from healthy subjects and patients with varicose
veins: Information categorisation approach based on intrinsic mode functions and entropy computation. Med Eng Phys. 2015 Jun;37(6):553-9.
doi: 10.1016/j.medengphy.2015.03.020.
Klonizakis M, Alkhatib A, Middleton G. Long-term effects of an exercise and Mediterranean diet intervention in the vascular
function of an older, healthy population. Microvasc Res, 2014 Aug 7;95C:103-107.
Klonizakis M, Moss J, Gilbert S, Broom D, Foster J, Tew GA. Low-volume high-intensity interval training rapidly improves cardiopulmonary
function in postmenopausal women. Menopause. Menopause, 2014 Oct;21(10):1099-105.
Alkhatib A, Klonizakis M. Effects of exercise training and Mediterranean diet on vascular risk reduction in post-menopausal
women. Clin Hemorheol Microcirc. 2014;57(1):33-47.
Khan AA, Klonizakis M, Shabaan A, Glynne-Jones R. Association between pretreatment haemoglobin levels and morphometric characteristics
of the tumour, response to neoadjuvant treatment and long-term outcomes in patients with locally advanced rectal cancers.
Colorectal Dis. 2013 Oct;15(10):1232-7.
Huedo-Medina TB, Kirsch I, Middlemass J,
Klonizakis M, Siriwardena AN. Effectiveness of non-benzodiazepine hypnotics in treatment of adult insomnia: meta-analysis
of data submitted to the Food and Drug Administration. BMJ. 2012 Dec 17;345:e8343.
Klonizakis M. Studying the cutaneous microcirculatory response during upper-limb exercise in healthy, older, sedentary people.
Clin Hemor Microcirc 2011; 48: 1-7.
Yeung JMC, Klonizakis M, Lingam K, Manning G, Donnelly R. Effects of Lower Limb Angioplasty on Endothelial-Dependent and -Independent
Microvascular Reactivity, Eur J Vasc Endovasc Surg Extra 2011; 22: e52-54.
Tew G, Klonizakis M, Crank H, Briers D, Hodges G. Comparison of laser speckle contrast imaging with laser Doppler for assessing
microvascular function. Microvasc Res 2011 Jul 22.
Klonizakis M, Winter E. Effects of arm-cranking exercise in cutaneous
microcirculation in older, sedentary people. Microvasc Res 2011 May; 81(3): 331-6.
Tew G, Saxton JM, Klonizakis M, Moss J, Ruddock A, Hodges G. Aging and aerobic fitness affect the contribution of noradrenergic
sympathetic nerves to the rapid cutaneous vasodilator response to local heating. J Appl Physiol 2011 May; 110(5):1264-70.
Klonizakis M, Manning G, Donnelly R. Assessment of Lower Limb Microcirculation: Exploring the Reproducibility and Clinical
Application of Laser Doppler Techniques. Skin Pharmacol Physiol 2011 Jan 5; 24(3):136-143.
Tew G, Klonizakis M, Moss J, Ruddock A, Saxton J, Hodges G. Role of sensory nerves in the cutaneous
vasodilator response to local heating in young and older endurance-trained and untrained men. Exp Physiol 2011 Feb;96(2):163-70.
Tew G, Klonizakis M, Moss J, Ruddock A, Saxton J, Hodges G. Reproducibility of cutaneous thermal hyperaemia assessed by laser
Doppler flowmetry in young and older. Microvasc Res 2011 Mar; 81(2):177-82.
Klonizakis M, Lingam K, Manning G, Donnelly R. Characterising the Two-Course of Microvascular Vasodilator Responses Using
LDF and Iontophoresis: Effects of Iontophoretic Charge, Posture and Venous Disease. J Pharmacol Toxicol Methods 2011 Jan-Feb;
63(1):115-118.
Klonizakis M, Tew G, Michaels J, Saxton J. Effects of upper-limb exercise on lower-limb cutaneous microvascular function in
post-surgical varicose-vein patients. Eur J Appl Physiol, 2010 Aug; 109(6): 1221-1224.
Tew G, Klonizakis M, Saxton J. Effects of ageing and fitness on skin-microvessel vasodilator function in humans. Eur J Appl
Physiol, 2010 May; 109(2): 173-181.
Klonizakis M. Presenting Microcirculation Using Laser Doppler Imaging (in Greek) Iatriko Vima, 2009 December -2010 January,
121: 34-37.
Kerr S, Klonizakis M, Glynne-Jones R. Suppression of the postoperative neutrophil leucocytosis following neoadjuvant chemoradiotherapy
for rectal cancer and implications for surgical morbidity. Colorectal Dis, 2010 June; 12(6):549-54.
Klonizakis M, Tew G, Michaels J, Saxton J. Effects Of Chronic Treadmill Exercise on Cutaneous Microvascular Function in Post-Surgical
Varicose Vein Patients. Microvasc Res, 2009 June; 78(1):67-70.
Klonizakis M, Tew G, Michaels J, Saxton J. Impaired microvascular endothelial function is restored by acute lower-limb exercise
in post-surgical varicose vein patients. Microvasc Res, 2009 Mar; 77(2):158-162.
Klonizakis M. The Use of Magnetic Resonance Imaging in Cardiovascular Studies: A Case Study for Mitral Regurgitation. WSEAS
Trans Maths Comp in Biol and Med, April 2006; 3(2): 311-316.
Klonizakis M, Yeung JMC, Nash R, Lingam K, Manning G, Donnelly R. Contrasting Effects of Varicose Vein Surgery on Endothelial-Dependent
and -Independent Cutaneous Vasodilation in the Perimalleolar Region. Eur J Vasc Endovasc Surg, April 2006; 31(4):434-438.
Klonizakis M. Quantification of Mitral Regurgitation Using Magnetic
Resonance Imaging. WSEAS Trans in Biol and Biomed, July 2005; 3(2): 274-279.
Klonizakis M, Yeung JMC, Nash R, Lingam K, Manning G, Donnelly R. Effects of Posture and Venous Insufficiency on Endothelial-Dependent
and -Independent Cutaneous Vasodilation in the Perimalleolar Area. Eur J Vasc Endovasc Surg, 2003; 26: 100-104.
Published Abstracts
Klonizakis M. Effect of ageing and fitness on skin-micro-vessel vasodilator function in humans. J Vasc Res, 2011; 48 (Supp.1):
36.
Sharma S, Moffat D, Christopoulos C, Klonizakis M, Wellsted D, Gorog DA. Global thrombotic status predicts cardiovascular
events in end-stage renal failure. Eur Heart J, 2010; 31(Suppl.1): 971.
Shaaban A, Khan A, Klonizakis M, Mawdsley S, Anyamene N, Denton A, Glynne-Jones R. The impact of pre-treatment haemoglobin
and tumour length on disease free survival and local recurrence in rectal cancers treated with pre-operative chemo-radiotherapy.
Annals of Oncology, 2010; 21 (suppl. 6): 59-60.
Klonizakis M, Tew G, Michaels J, Saxton J. Effects of Exercise Training on Skin Blood Vessel Function in Post-surgical Varicose
Vein Patients. Clin Hemor Microcirc, 2009; 42(3): 203.
Yeung J, Klonizakis M, Nash R, Lingam K, Manning G, Donnelly R. The Effect Of Diabetes On The Cutaneous Microcirculation In
The Feet Of Patients With Intermittent Claudication:- A Role For Deterioration? J Vasc Res, 2002; 39 (Suppl.1): 589-590.
Yeung J, Klonizakis M, Nash R, Lingam K, Manning G, Donnelly R. Upright posture impairs microvascular vasodilation in
patients with varicose veins: Possible role in ulcer formation. Clin Sci (London), 2002; 103(1): 7P-8P.
Klonizakis M, Yeung J, Nash R, Lingam K, Manning G, Donnelly R. Upright Posture Impairs Microvascular Vasodilation In The
Lower Limb In Patients With Isolated Superficial Venous Insufficiency. J Vasc Res, 2002; 39 (6): 547.
Book
Klonizakis M. Cutaneous Microcirculation and Lower-Limb Venous Disease. Lambert Academic Publishing, Saarbrücken, Germany,
ISBN: 978-3-8383-2995-6.
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