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Audrey Hardy - Rachel Ames

Monica Quartermaine - Leslie Charleson

Alan Quartermaine - Stuart Damon

Ruby Anderson - Norma Connolly

Amy Vining - Shell Kepler

Lila Quartermaine - Anna Lee

Bobbie Spencer Jones Cassadine - Jacklyn Zeman

Tony Jones - Brad Maule

Robin Scorpio - Kimberly McCullough

Luke Spencer - Anthony Geary

Mac Scorpio - John J. York

Ned Ashton - Wallace Kurth

Jason (Quartermaine) Morgan - Steve Burton

Felicia Jones - Kristina Wagner

Brenda Barrett Jacks - Vanessa Marcil

Lucy Coe - Lynn Herring

A.J. Quartermaine - Sean Kanan

Dr. Kevin Collins - Jon Lindstrom

Katherine Bell - Mary Beth Evans
                              
Sonny Corinthos - Maurice Benard                              
                               
Laura Spencer -  Genie Francis                                 
                                
Lucky Spencer - Jonathan Jackson                                
                               
Justus Ward - Joseph C. Phillips
                                                                
Keesha Ward - Senait Ashenafi                            

Edward Quartermaine - John Ingle                                

Tom Hardy - Matthew Ashford                         

Jax -  Ingo Rademacher                        
                              
Dara Jensen -  Vanita Harbour
                                
Carly Roberts - Sarah Brown
                                                                
Stefan Cassadine - Stephen Nichols                              
                                
Nikolas Cassadine - Tyler Baker                               

Miranda - Leslie Horan                              

                                   

Recurring Characters

Simone Hardy - Felecia Bell

Dr. Gail Baldwin - Susan Brown                                                       
                                                          
Gina Williams - Stephanie Dicker
                                                         
Alexis Davis - Mamcy Lee Grahn                                                        

Mike Corbin - Ron Hale                                                        

Lee Baldwin - Peter Hansen
                           
Reginald Jennings - Stephen Kay
                            
Maria - June Lockhart                            
                               
Bryan - Bryan Moeller                            

Virginia Benson - Lois Nettleton
                            
John Jacks - Peter Renaday
                              
Jake - Stella Stevens

Emily - Amber Tamblyn                            
                              
Jane Jacks - Barbara Tarbuck
                            
Pierce Dorman - Tuc Watkins