Here is more information on supplements that have been tried. Please contact me if you have more information to add.

--Vitamin B-Complex- 50 mg. daily (with 1000 mcg B-12) - this aids in the cell formation and is required for all proper digestion aspect; energy production, helps to maintain the health of the nerves, skin, eyes, hair, liver and mouth, as well as healthy muscle tone in the GI tract, proper brain function. Many of the miscellaneous symptoms we experience are from B-deficiencies, especially B-6 and B-12.

--Biotin - 800 mcg twice daily - aids in cell growth, carbohydrate fat and protein metabolism, as well as in the utilization of B-vitamins. It is expensive, but worth it to ensure proper utilization of the B's.

--Vitamin C- 500-2000 mg. daily, (sustained release is the best), used to regulate the gut, bladder function, it is essential for nerve conduction, aids in interferon (anti-viral activities) production, and is needed for metabolism.

--Vitamin E - 200-400 IU daily. It is an anti-oxidant that improves oxygen utilization, boosts immune system response (normally lowers with aging).

--Calcium Complex - 1000-2000 mg. daily (at least 1500 for post menapausal women). This is active in bone formation and muscle functioning; provides energy, it is involved in the activitiesof some enzymes. Calcium is critical along with potassium for healthy muscle functions, and heart functions.

--Magnesium - 400-1000 mg. daily - In one study I read, there was significantly low magnesium levels in FMS individuals and people with FMS in their pain and tenderness levels. Magnesium works to inhibit the action of Excitatory amino acids. Increased amino acids can lead to increased pain and discomfort. Low calcium, magnesium, potassium leads to the cramping of muscles, especially in the legs.

--Potassium - 99 mg. daily - aids in the proper muscle functions. Needs to be taken with magnesium.

--Malic Acid - 1200-1400 mg. daily - (not all at the same time). It is important to the production of energy in the body. Depletion has been hypothesized to be a major cause of physical exhaustion. It must be taken with magnesium. The product that I and many people with FMS take is Magnesium Malate from Source Naturals, which has 825 mg. Malic Acid, and 152 mg. of Magnesium. MA lessens pain, and gives more energy.

--Co-Enzyme Q 10 - 100-200 mg. daily - It is a powerful anti-oxidant; it has anti-aging effects, aids the cardiovascular system (by protecting the heart increasing circulation), production of energy and peridontal health.

--L-5-HTP- (5 Hydroxytryptophan) touted as the "Serotonin Solution". 200-300 mg. daily. There are several advantages of considering 5-HTP in that it is not degraded, it easily passes through the blood/brain barrier so that it can be utilized. 5-HTP is virtually a "guided missle" directly targeted to increase brain serotonin!!!

--Glucosamine and Chondroitin - Start up phase 3 tablets am and pm with meals. Maintenance phase 3-6 tablets daily with meals according to personal needs. Stated to regenerate and maintain the natural lubricating fluid in joints and cartilage. One physician stated that it also helped to calm the gut, but the is only hearsay, not on the list of effects of the supplement by the manufacturer.