leucine as an appetite suppressant
fodmap: fermentable oligo- di-
and mono-saccharides, and polyols
albumin, protein quality and fluid retention
gelatine, broths, grape juice,
phenols and albumin
problems with kefir and fermented vegetables
fasting cycles induct regeneration of the white blood cells and the islet cells in the pancreas
17th october 2017, i have just had a bad migraine/virus and didn't eat for three days, there's a flu going around so severe it can actually kill people i read in the news..
i didn't have loose stools or stomach pain, dry retched once, but all in all was reasonably comfortable which i attribute to the not eating, i also very distinctly did not feel hungry
i feel the fasting period did me good, the secret is to keep a lining of sugar on the stomach so you don't lose your good microbiome, i do that by boiling water and adding 50ml of coconut water (no more !), a teaspoon of jam and possibly a teaspoon of cream ?
i think there is something to fasting when ill or to lose weight or induct regeneration at the stem cell level of the immune system, one of the suprising things about holocast survivors is an unchanged life expectancy for women and even slightly increased for men !
there are so many overweight young women about now thinking their condition is revresible, but the skin stretches creating a nightmare and possible need for surgery when weight is actually lost, fasting is a very effective way of losing weight if done with care !
its also recommended as a way to "reboot" the immune system after chemo !
you can be short of a nutrient and get by, but you age much more rapidly !
this theory is strongly supportive of the combined compendium and BCD approach as the compendium attempts to meet as broad a spectrum of mineral and vitamin needs as practically possible while the BCD supplies a more comprehensive range of nutrients, sugars/carbohydrates and proteins in a fashion that tamps biofilm but provides superior nutrition !
one of the things bruce ames says is that the RDA range of vitamins and minerals is only what is needed to supply nutrients for essential functioning, that to to get out of the area of accelerated aging there is another huge partially unkown range of food factors (like new work on polyphenols and anti-oxidants is beginning to show) that you need !
neither the compendium or the BCD by themselves are sufficient, but together they are mutually reinforcing !
people who select or eliminate food on an irrational basis varying from any number of stupid weight loss diets, supposed health diets, fast foodism, raw foodism, veganism (unless you are donald watson lol), fruitarianism , to the various permutations of anorexia are driving themselves into metabolic syndromes of various sorts and an early death or long and painfull disability from their weakest link
unfortunately the above applies to the way most people eat now !
I am almost afraid to ask but I need to. Someone on pecanbread
mentioned that I needed to avoid the avoids for my son's blood type.
I looked at the book. My son is type A. Which is basically a grain based
diet. The only meats not on his avoids are chicken and turkey in
limited amounts. He is supposed to pretty much avoid eggs as well-- low
protein, low fat. Take out grains, take out protein, take out fat,
take out lots of fruit and all sugars and you have...not enough to
sustain a two year old. I guess I am hoping there is nothing to it.
If there is...should I forget SCD with him?
my reply:
in theory a certain blood type predisposes you to accepting certain antigens as per what is on the red blood cell, as self
stretching that to cover possible food antigens getting into the blood by promoting certain food groups compared to others is the usual insanity i've come to expect from the urban nutrition mythology that prowls around the web
a diet relating blood groups and food is nonsense because you cannot create categories of antigenic specific foods
this study showed no difference between type A and type O eating a plant based diet
interestingly dupont has probiotic product it claims is bile and acid resistant and capable of enhanced binding to A, B and/or O blood type antigens, which by its mucosal glycan targets shoots any blood type diet down in flames !
quoting from the dupont patent
“ it is thought that as the glycan structures of the ABO blood groups are abundant in the mucosa and serve as bacterial adhesion sites and nutrient sources, stronger binding to one or more ABO antigens by a probiotic bacterium will improve its colonization of the bacterium in the gastrointestinal tract by enhancing its interaction with the mucosa
the probiotic bacterium may also demonstrate enhanced health effects by blocking the adhesion and invasion of certain pathogenic microbes which also bind to ABO antigens
a probiotic bacterium which adheres to an ABO antigen could also enhance the probiotic responses by providing tighter and longer-lasting contact between the host cells and probiotics
it could further provide the host easier access to any beneficial metabolites produced by the probiotics when probiotics are colonized tighter and more long-lasting ”
covid-19 differentiates between blood types
the easy way to start the BCD is to eliminate grains and potatoes and start working enzymes in, the houstonni zyme prime and maybe candex and oreganol for intestinal yeast
food has to be sourced and evaluated according to a number of factors, not just scd sugar propensity if you are to get adequate nutrition for your child
just start doing a few things, forget the introductory diet and you will make progress
also get some whole body exposure of high solar noon sun
october 2008
d'adamo, his blood type diet must have run out of flakes because he's generated a new slant * genohype *
if the BCD ever appears in the daily mail endorsed by a celebrity, shoot me, the body snatchers must have entered my brain
now i know my blood type
from donating blood
as a help to lower my iron levels
O positive
which according to d'adamo is the hunter type
i
know he's screwed because i do better on medium to low protein and low iron in my diet
though
i
do
hunt
: o )
i'm not saying there's no sense to what he says, it's a bit like astrology, sometimes sensible advice given in a random context !
if you disregard what he says in the sense of relating to a specific blood type but rather apply it generally, pretty much like good astrology you may get some benefit ; o )
however the theory behind the blood type diet is invalid !
different antigens and combinations will alter the contrast to the antigens of different viruses, bacteria and parasites and hence offer differing levels of assistance to the immune system in identifying certain pathogens compared to others and also affect autoimmunity selectivity
regional distribution of blood types is a combination of migration, disease and autoimmune selectivity
histo-blood group antigens promote binding of norovirus and helicobacter pylori cells to intestinal cells and recently it has been discovered that blood type A may predispose to some rotavirus infections
blood type O has the lowest risk of pancreatic cancer and type B has the highest risk
“ compared to people with type O blood, those with type A have a 32% higher risk of pancreatic cancer, those with type AB have a 51% higher risk and those with type B have a 72% higher risk ”
type O blood cells bond weakly to the RIFIN protein secreted by the malarial plasmodium falciparum parasite, thus giving people who get infected by this parasite with type O much less clotting and a huge comparative advantage over people with type A in this situation !
In people with blood type O, scientists found that cholera toxin hyperactivates a key signaling molecule in intestinal cells. High levels of that signaling molecule lead to excretion of electrolytes and water - in other words, diarrhea. Cholera is marked by severe diarrhea that can lead to dehydration, shock and even death.
so basically there are differences in immune and other functions and cellular responses between blood types, none of which seem to particularly relate to d i e t ! : o)
some good news , i’m O+
an enzyme pathway in the hypothalamus regulating appetite servos on protiens especially leucine
so the brain is actually looking for protein satiety
the ratio of leucine in meats say compared to wheat is 5:1 so you can see that with a high carb/low protein diet you are never going to feel full cause you will be craving more protein and leucine from the servo
mechanism in the hypothalmus going open loop
“ It appears that leucine stimulates a signaling pathway somewhat like the hormone insulin It has been debated whether the action of leucine was simply confused with the action of insulin. Our research shows that there is a unique role of leucine, and that it runs almost parallel to insulin. It appears that leucine stimulates the first step in protein synthesis. ” study
leucine is a branched chain amino acid
as an amino acid supplement it appears to have the usual amino-acid biofilm feeding issues so is not recommended as an amino acid supplement or filler in capsules e.g. the allergy research niacin
e.g. fruit with cream (double cream yum!) which radically changes the sugar absorption profile and glycemic heft !
the glycemic index is a carbohydrate ranking system and typical of the pseudo nutritional science that can emerge from the university nutritional schools
the media have been pushing this nonsense for years and when a study comes along that shows different people can have very different, even opposite glycemic responses to a particular food with the microbiome as an important factor, nary a peep is heard ! : o(
____________________
the glycemic index is flawed because the way it is tested is unnatural and doesn't match the real world conditions of eating and gastric health
the fruit/vegetable concerned is given by itself after a 12 ? hour fast and then the blood sugar measured.
to give a fruit or vegetable after a fasting period like that is going to promote bad gut flora which will promote early release of single sugars, in fact what the glycemic index may be measuring is fruits and vegetables that are more resistant to consumption by gut biofilm
other huge variables are the degree and type of cooking, the stage of season that the food is harvested, how long it has been stored and any pre processing, all of which can change the glycemic index in the order of 10 to 100%
In real life, fat and protein with the meal/fruit/vegetable, and adequate trace minerals like chromium strongly modulate blood sugar and insulin levels favourably
there is something to the idea of the zone diet in reducing insulin peaks, but it all boils down to eating protein and fat with fruits and vegetables to slow the insulin rise and reduce the peak.
again chromium gtf is instrumental in reducing insulin resistance.
i always have additive free double cream with cooked/pasturized fruit
they have the wrong model of the digestive system, like the stomach is a vat only controlled by human digestive juices
what about biofilm and the microbiome?
____________________
the insulin index, while better than the glycemic index also suffers from not accounting for food combinations and biofilm
____________________
glucose profile, yet another index!
they just try and create this single measurement dimension but in fact there are a hundred significant ones, bet they are not measuring biofilm toxins or an allergenic response to pasta for a start!
it's a maladapative plagiarism of the SCD diet and at an abstract level is similar scientific theory to the SCD and BCD diets, however the way it is implemented is crazy, food exclusions are based too much on theory and guesswork and not practical results, any food is such a complex interaction of many factors that practical effect (though guided by theory) has to be foremost !
one fundamental difference is the BCD and SCD diets focus on the exclusion of fermentable long chain sugars and the inclusion of short chain sugars . . FODMAP has some sort of scattergun approach it's hard to work out the reasoning b e h i n d ! . . ! : o ) (
“ the diet in part involves cutting back on wheat, onions, milk, icecream,
apples, honey and stone fruits. legumes were also found to cause pain
often they are sugars and carbohydrates that are not absorbed when they pass through the bowel and when they get into the colon they can ferment and produce gas and pain ”
above quote from dr. richard gearry, otago university new zealand
my comment:
i am looking further at this but the implication for BCD appears to be that there is an upper limit to the quantity of pasturized fruit eaten which i do find to be the case from both a blood sugar and gut health point of view, but with the compendium and BCD i do seem to be able to eat quite a bit !
“ fructose. this is present in the diet as a free monosaccharide, as a constituent of the disaccharide, sucrose, or
polymerized as fructans.
when fructose is ingested as sucrose (table sugar is sucrose), or in equimolar combination with glucose, it is absorbed with an efficiency estimated to be 85% that of glucose because it is of high capacity and glucose-facilitated.
fructose in excess of glucose (free fructose) can also be absorbed by a low-capacity glucose-independent facilitated transport.
if the load of free fructose is sufficiently large, malabsorption of fructose is universal. however, about 30% of the population exhibits a very limited ability to absorb any free fructose ”
when i look at the foods excluded or preferred on the low fodmap diet, it's sorta half ways sensible, but no more than half !
i strongly suspect it to be an attempted medical answer to the SCD, but they have chosen the wrong end of the band of saccharides as fermenting and basically is a quite dated pre-enzyme approach that as per medical versions of anything, makes sure they don't lose custom !
what interested me is that when i have added vinegar to warm wallaby carcass broth you get the same effect of a white albumin precipitate
one function of albumin is to control the 'osmotic pressure' that keeps fluid in the blood and out of tissue
it is made by the liver on demand and presumably dietary albumin also is important
low albumin causes endema or fluid retention and people on low protein diets are particularly prone to developing this because albumin manufacture by the liver is very sensitive to protein quality and completeness
in fact having seen how trim people become eating high quality protien and getting good protein completeness and balance from different sources of protein like different meats from different animals and dairy cheeses and also whole carcass broths and possibly wheys (wheys have digestion issues), most people today are suffering endema to some degree and its part of the obesity explosion.
i suspect that the notions of essential and 'inessential' proteins become blurred in this and for adequate albumin production many of the so called 'inessential' proteins are 'essential'
i have a bottle of Llyods organic harvest muscatel grape juice and
will try a small amount diluted in water and pasturised to about 75C
----------------------------
Mutagenicity of white grape juice in the Ames test.
Patrineli A, Clifford MN, Walker R, Ioannides C.
Molecular Toxicology Group, School of Biological Sciences, University
of Surrey, Guildford, UK.
The mutagenicity of commercially available white grape juice was
evaluated in the Ames mutagenicity test. Grape juice elicited a
positive mutagenic, response in Salmonella typhimurium strain TA104
and a weaker response in strains TA97, TA98, TA100 and TA1530. The
mutagenic response was evident in the absence of an activation system
and inclusion of such a system did not influence mutagenicity. The
grape juice-mediated mutagenic response was not due to histidine
residues in the juice or likely treatment with sulfite. Moreover,
freshly prepared grape juice displayed a similar mutagenic response.
Three different brands of commercially available white grape juice
were investigated in the Ames test; they all provoked a clear
positive mutagenic response, but the degree of mutagenicity differed
and could not be attributed to differences in the content of solids.
It is concluded that grapes contain direct-acting genotoxic component(s).
Mutagenic substances in red and white wine in Chile, a high risk area
for gastric cancer.
Bull P, Yanez L, Nervi F.
Chilean home-made and commercial wines were analyzed for the presence
of mutagenic substances using the Salmonella mutagenicity test with
preincubation. Strains TA98 and TA100 were used in the absence and in
the presence of S9 mix. 90% of red wines from a total of 30 samples
and 54% of white wines from a total of 22 were found to be mutagenic.
In all cases, S9 mix did not affect the mutagenicity of the samples.
At least in one case, more than one mutagen was present, since the
mutagenicity with TA98 could be selectively inactivated without
affecting that with TA100. This study supports the hypothesis that
wine consumption may be an important risk factor for upper
gastrointestinal cancer, particularly for adenocarcinoma of the
stomach, which is highly prevalent in Chile.
------------------
ouch the bioflavanoids in wine (rutin) are genotoxic
-----------------
Mutagenic activity in the wine-making process: correlations with
rutin and quercetin levels.
Rueff J, Laires A, Gaspar J, Rodrigues A.
Faculty of Medical Sciences, UNL, Department of Genetics, Lisbon,
Portugal.
Mutagenic activity was monitored during the time course of the
vinification process of a Portuguese red wine using the Ames assay.
Dependence upon faecalase treatment for detection of mutagenicity was
evaluated concurrently with HPLC analysis of the flavonoids rutin and
quercetin. Rutin (quercetin-o-3-rutinoside) is liberated from the
grapes during the first 10 days of the process and is hydrolysed as
the vinification process proceeds. This explains the levels of the
free quercetin in the wine and mutagenicity in the absence of
faecalase treatment. Mutagenicity in the presence of faecalase during
the first 26 days of the process correlates with the levels of rutin,
and in the absence of faecalase the highest mutagenic activity
detected (160th day) coincides with the highest level of free
quercetin. Our results do not rule out the possibility that other
mutagens are present in wines, in particular oxidative-type mutagens.
------------------
glycosides hydrolysised to mutagenics by gut flora enzymes
Many substances in the plant kingdom and in man's diet occur as
glycosides. Recent studies have indicated that many glycosides that
are not mutagenic in tests such as the Salmonella test become
mutagenic upon hydrolysis of the glycosidic linkages. The Salmonella
test utilizes a liver homogenate to approximate mammalian metabolism
but does not provide a source of the enzymes present in intestinal
bacterial flora that hydrolyze the wide variety of glycosides present
in nature. We describe a stable cell-free extract of human feces,
fecalase, which is shown to contain various glycosidases that allow
the in vitro activation of many natural glycosides to mutagens in the
Salmonella/liver homogenate test. Many beverages, such as red wine
(but apparently not white wine) and tea, contain glycosides of the
mutagne quercetin. Red wine, red grape juice, and tea were mutagenic
in the test when fecalase was added, and red wine contained
considerable direct mutagenic activity in the absence of fecalase.
The implications of quercetin mutagenicity and carcinogenicity are
discussed
M. replies in a post titled 'gelatin and phenols'
I know andrew has discussed gelatin in previous posts. I was
reading about wine and it seems that gelatin is an agent used to
reduce phenols in wine and juices. I also read it as one of the
substances to be used in case of accidental phenol ingestion:
"Victims who are conscious and able to swallow should be given 4 to
8 ounces of milk, egg whites, or gelatin solution; if the patient is
symptomatic, delay decontamination until other emergency measures
have been instituted"
culled from: http://www.atsdr.cdc.gov/mhmi/mmg115.html
"Question: How do I use gelatin?
Answer: Gelatin is used in juices for reaction with polymeric
phenols at dosage rates of 2 – 8 ounces per 1000 gallons. A 5%
slurry is better for adding gelatin to the juice. The gelatin should
be hydrated properly in water with slow mixing."
culled from:
http://www.filtermaterials.com/Gusmer/techsupport/FaqList.asp?deptId=3
Everyone in my family is reactive to phenols. I wonder if these
same chemical principles gelatin is used for the above items would
also work in the body. Egg whites were also mentioned frequently in
reducing phenols (albumin). Phenols must rapidly denature these proteins?
I wonder if joint problems are due to being phenolic sensitive
(impaired) and the phenols are bonding to the collagen sites of the
body, such as joints,synovial fluid,etc. My daughters both walked
on their toes and my youngest one still has a rigidity to her
limbs. Perhaps increasing gelatin consumption would be an interesting experiment.
This denaturing of proteins may also explain the genotoxicity of
grape juice and wine. The article andrew posted did mention querceting and rutin (both highly phenolic).
Maybe people taking those people taking turmeric pills should reconsider that too.
my reply
phenols are aromatic alchohols and probably toxic as a class which
would be abated by predigestion in the gut by no fenol or enzymes from gut flora
have you tried the houstonnni no fenol?
phenol problems would be tautological with leaky gut and gut flora dysbiosis
phenols preciptiate protiens by binding to them making gelatin an effective remover of them
that would be another reason why broths were used as a food for the
ill and the elderly with thier errant gut flora and leaky guts
broth with a meal would bind up phenols
bit of course todays soups are not broths but sewerage
it would be interesting to know if phenol issues were related to
fluid retention since phenols in the blood might bind with albumin
so broths might reduce fluid retention both by removing phenols while
in the stomach and also being a source of albumin
my exerience of gelatin is its not the real mcCoy and whole carcass
(wallaby lol) broth is needed with all the other food factors
gelatin just does not seem to cut the ice
yeah the gelatin broth helped my back a lot i think, the disk was
goign awol when i had a preriod of going without the broths cause of
the hassle making them
my reply
scd, grape juice and gelatin
its interesting that gelatin could 'filter' phenols in grape juice and
that scd emphasises both
i wonder if thats something sidney haas worked out experentially
my reply
i wonder if you'd get away with gelatin if you took some b vits
a b multi with maybe some added b6 to help the body process the gelatin
houstonni pep can help to
unfortunately having feral broth makes you realise how poor these store
bought animals are
My daughter's stool was alkaline on her stool analysis testing.
Which in the presence of all the yeast and bacteria was not a good
sign. I have not tested her since then. That is interesting that
supplementing in an alkaline environment is not good. I think I
should probably test her ph. Where are people getting strips?
Which is better urine or saliva or maybe do both?? Also, anyone
hear of Liver Life - I know SCD illegal, but another product I have heard people use.
my reply:
look you have a problem skipping over important concepts and its
messing your application of problem solving
what you skipped over was the notion of 'servo'
the water level in a lavatory (bathroom? in the usa) cistern is a servo
the water level rises until the float turns it off, that is, it works
to keep a certain water level in the cistern
its the same with body and PH, there are a multitude of biochemical
servo systems maintaining different ph's in different body and
biochemical compartments and in general the ph is a secondary and not
primary effect (except with the stomach and upper intestine)
all you are doing with ph testing is saying the servo systems are not
working..................
you already know that
you are better to focus on causes like gut bacterial and flora dysbiosis
you cannot rectify servo systems with alkaline or acid supplements
with the exception of the stomach and upper intestine where they may
be of some use but really its better to use the servo's like optizinc helps turn on stomach acid
lihtium acts as an anti servo turing down stomach acid
the human craving for over simple theories and remedies is an endless
reef of destruction as history shows
enjoy the reef, its better to be sailing though
C. writes
I've used a variety of fermented vegetables, kefir, and kombucha tea
to get probiotics. I finally figured out that we were having an
adverse reaction to all fermented foods, kefir included.
Too bad - we really liked them and there should be a lot of great health benefits.
Anyway, you can get kefir culture from a website for the Body Ecology
diet. I would think that it's water grains since they use it to
culture young coconut water. Also, I've read that you can use milk
grains to culture non-milk beverages. The first few batches take
longer to culture. There's more info at Dom's kefir site.
S. replies
I should mention that we also had a range of reactions to 6 months
of probiotic foods, none of them good. We used cultured veggies and
coconut kefir cultured both "wild" (from the native flora) and with
our own probiotics. The reactions ranged from "nothing" to a
severely acid gut condition. My son ended up with a d-lactate
condition, an acidifying of the gut which can lead to pancreatitis.
He also wasn't digesting all the raw cultured veggies very well -
his digestion just wasn't that strong. We switched to SCD and easily
digested foods, and he did much better.
Elaine Gottschall says to avoid "wild" cultured foods, and after our experience I agree.
Also, be aware that the BED cultures aren't dairy-free.
S. writes
Re: Casein-free kefir grains?
I was able to find some water grains on a kefir board. It made "okay"
kefir using water with dried fruit and sugar, but since my son is
allergic to all fruits, and sugar gives him yeast, I was never able to
give it to him. The kefir never reached the point of having all the
sugars digested by the kefir grains without much of the kefir turning
alcoholic. It was always too sweet or too alcoholic. It seemed like it
always had some amount of alcohol, which I was not comfortable giving
to my 3-year-old.
Another reason I hesitated was that there was no way to find out what
was in the grains. At some point they're derived from milk grains.
These are completely homegrown, with no documentation of what's in
them. That made me nervous too
veges have microbial accessible sugar and the flora you ingest with the fermented vegs is going to be very good at biofilm construction
and kefir also is entirely biofilm, if you have ever pushed a kefir grain around with its squishy polysaccaride walls
yeast seems to be intrinsic to biofilm construction, or at least biofilm of any interesting 3d complexity
interesting to compare with yogurt which is not biofilm
coconut kefir could be downright dangerous, being breed as it is in the microbial resistant enviroment of coconut
integrating biofilm understanding into scd very much improves its coherence and functionality