Tufts Chemistry Department

Undergraduate Courses

1 Chemical Fundamentals. Atomic and molecular structure; intermolecular forces and states of matter; the relation of structure and bonding to the physical and chemical properties of matter; patterns of chemical reactions. Qualitative thermodynamics and equilibrium. Three lectures, one laboratory, one recitation. Only one of Chemistry 1, 11, or 16 may be counted for credit. Members of the Department

2 Chemical Principles. Physical and chemical equilibria, properties of solutions, thermochemistry and thermodynamics. Chemistry of selected elements. The laboratory includes preparative inorganic chemistry. Additional topics may include electrochemistry, nuclear chemistry, coordination chemistry, organic chemistry, polymer chemistry, biochemistry. Three lectures, one laboratory, one recitation. Prerequisite: Chemistry 1, 11, 16, or consent. Only one of Chemistry 2 or 12 may be counted for credit. Members of the Department

8 Environmental Chemistry. An introductory course designed primarily to give nonscience majors an appreciation of basic chemical principles underlying the causes of and possible solutions to current environmental problems. The concept of equilibrium in complex systems; thermodynamic limits and kinetic realities. Case studies from current literature. Prerequisite: High-school chemistry. Spring 2000 and alternate years. Kenny

11, 12 General Chemistry. Topics covered are the same as in Chemistry 1 and 2, but discussed in greater detail and with a higher degree of mathematical rigor. Designed to provide a strong foundation for advanced courses in chemistry. For well-prepared students intending to be science majors. Some familiarity with elementary calculus concepts assumed. Three lectures, one seminar on frontiers in chemistry, one laboratory, one recitation. Three courses. Prerequisites: Score of at least 3 on the AP chemistry exam or consent; Mathematics 11 (may be taken concurrently). Only one of Chemistry 1, 11, or 16 and one of Chemistry 2 or 12 may be counted for credit. Members of the Department

16 Chemistry of Materials. An introductory course investigating the fundamentals and principles of chemistry through exploration of modern materials, e.g., thin films, superconductors, ultrasmall structures, modern electronics and photonics. Topics include atomic and molecular structure, intermolecular forces, ionic and covalent bonding. This one-semester course may be used in conjunction with Chemistry 2 to fulfill the basic chemistry requirement for a chemistry major. Three lectures, one recitation, one laboratory. Prerequisite: Good background in mathematics. Only one of Chemistry 1, 11, or 16 may be counted for credit. Spring. Members of the Department

31 Physical Chemistry I. Fundamental principles of chemical thermodynamics and kinetics and their application to the energetics and rates of chemical reactions in the gaseous and solution states. Three lectures. Prerequisites: Chemistry 2 or 12, Mathematics 12 or equivalent, and Physics 2, 4, or 12, or consent. (Physics may be taken concurrently.) Fall. Members of the Department

32 Physical Chemistry II. Four main topics of modern physical chemistry: elementary wave mechanics and chemical bonding, elementary statistical thermodynamics, elementary mathematical models for problems in molecular structure, topics in chemical kinetics. Three lectures. Prerequisites: Chemistry 2 or 12, Mathematics 12, and Physics 2, 4, or 12, or consent. Spring. Members of the Department

33 Beginning Physical Chemistry Laboratory. Thermodynamic, kinetic, and electrochemical experiments. One laboratory. One-half course. Prerequisites: Chemistry 31 or concurrent registration. Fall.

34 Intermediate Physical Chemistry Laboratory. Spectroscopic, kinetic, and advanced physical-chemistry experiments. One laboratory. One-half course. Prerequisites: Chemistry 32 or concurrent registration. Spring

42 Analytical Chemistry. Course Material for Spring 2003 Introduction to methods of quantitative analysis. Data treatment; volumetric and gravimetric analysis; equilibrium and buffer chemistry; basic instrumental concepts of spectroscopy, chromatography, coulometry, voltammetry, and biosensors. For both chemistry and life science majors, as well as students enrolled in environmental studies. Three lectures, two laboratories. One and one-half courses. Prerequisite: Chemistry 2, 12, or consent. Spring. Kounaves

50 Survey of Organic Chemistry. One semester survey of organic chemistry. Topics include structure and bonding in organic molecules, spectroscopy, stereochemistry, reactivity, synthesis, polymer chemistry, and bioorganic chemistry. Will not fulfill the organic chemistry requirement for chemistry majors, premedical, predental, or preveterinary students. May not be taken for credit in conjunction with Chemistry 51 or 52. Students needing a laboratory should register for Chemistry 53. Three lectures. Prerequisite: Chemistry 2 or 12. Spring 2000 and alternate years. Members of the Department

51 Organic Chemistry I. Structure, bonding, stereochemistry, and reactions of carbon compounds. Mono- and polyfunctional compounds, aliphatic and aromatic structures. Synthesis, reaction mechanisms, electronic interpretations of reactivity, spectroscopy. Two 75-minute lectures, one recitation. One course. (Note: The laboratory course, Chemistry 53, is normally taken concurrently with Chemistry 51.) Prerequisite: Chemistry 2 or 12. Fall. Members of the Department

52 Organic Chemistry II. Continuation of the topics presented in Chemistry 51. Two 75-minute lectures, one recitation. One course. (Note: The laboratory course, Chemistry 54, is normally taken concurrently with Chemistry 52). Prerequisite: Chemistry 51. Members of the Department

53 Organic Chemistry Laboratory I. Experiments based on topics in Chemistry 51. One laboratory, one lecture. One-half course. Co-requisite or prerequisite: Chemistry 50 or 51. Fall.

54 Organic Chemistry Laboratory II. Experiments based on topics in Chemistry 52. One laboratory, one lecture. One-half course. Prerequisite: Chemistry 53. Co-requisite or prerequisite: Chem 52. Spring.

55 Advanced Synthesis Laboratory. Introduction to advanced laboratory techniques in synthetic organic and inorganic chemistry. Emphasis on synthetic methods that involve organometallics, catalysts, and enzymes. Techniques include inert atmosphere manipulations, chromatography, and spectroscopic analysis. Nine hours of laboratory. Prerequisites: Chemistry 52 and 54. Members of the Department

61 Inorganic Chemistry. Chemistry illustrative of the kinds of bonding in inorganic compounds, including discussions of ionic, covalent, electron-deficient, and coordination compounds. Three lectures. Prerequisites: Chemistry 31 and 52. Only one of Chemistry 61 or 161 may be taken for credit. Fall. Haas

91 Research I. Training in the methods of chemical research. Frequent conferences and library assignments. Open to qualified advanced students. At least fifteen hours per week of laboratory or research work in chemistry required. Prerequisite: consent. Pass-fail grading. Members of the Department

92 Research II. Continued training in the methods of research. At least fifteen hours per week of laboratory or other research work in chemistry required. Students write a report of research accomplished. Prerequisites: Chemistry 91 and consent. Members of the Department

Courses for Undergraduate and Graduate Students

131 Chemical Thermodynamics. A detailed application of the laws of thermodynamics to chemical and phase equilibria. Thermodynamics of solutions and solids. Introductory statistical thermodynamics. Three lectures. Prerequisites: Chemistry 31 and Mathematics 13, or consent. Spring 2002 and alternate years. Members of the Department

132 Chemical Kinetics and Dynamics. Study of chemical reaction rates in the gas phase and solution. Topics include kinetic models, experimental methods, molecular reaction dynamics, kinetic theory of gases, potential energy surfaces, and transition state theory. Prerequisite: Chemistry 32 or consent. Spring 2003 and alternate years. Members of the Department

133 Quantum Mechanics. Covers Schrödinger equation and basic quantized systems, statistical interpretation and uncertainty, perturbation theory, scattering, symmetries and invariances, approximation methods, energy calculations. Prerequisite: Chemistry 32; Mathematics 38 recommended. Fall. Members of the Department

134 Statistical Mechanics. Fermi-Dirac, Bose-Einstein, and Maxwell-Boltzmann statistics. Ensembles, most probable distribution, and fluctuations. Calculation of chemical potential from molecular constants; determination of equilibrium in gas-phase reaction systems; transport properties; simple theories of solids, liquids, and solution. Prerequisite: Chemistry 32; Mathematics 38 recommended. Members of the Department

135 Biophysical Chemistry. Thermodynamics of biochemical systems, biochemical and biological dynamics, biochemical spectroscopy and structure determination, statistical thermodynamics and transport properties, electrochemistry in the biological context, and membrane biophysics. Three lectures. Prerequisites: Chemistry 52 and 31. Members of the Department

136 Spectroscopy and Molecular Structure. Electronic, vibrational, and rotational energy levels of molecules, and transitions between these levels. Molecular symmetry. Time dependence and symmetry requirements of spectroscopic transitions. Born-Oppenheimer approximation, Franck-Condon principle, potential surfaces, other spectroscopic methods. Prerequisite: Chemistry 133 or consent. Spring 2001 and alternate years. Members of the Department

141 Instrumental Analysis. Course Information for Fall 2001. Theory, operation, and application of principal instruments used in chemical analysis and research. Selected special topics such as molecular, atomic, and mass spectroscopies; electrochemistry; and chromatography are included. Designed to acquaint the student with modern laboratory techniques used in all areas of chemistry. Prerequisites: Chemistry 31, 42, and 51, or consent. Fall. Robbat

142 Advanced Analytical Methods. Course Material for Fall 2002. In depth study of several modern specialized techniques and their application to current qualitative and quantitative problems in environmental, materials, and biochemical areas of analysis. Three lectures. Prerequisites: Chemistry 42 or 141, or consent. Kounaves

143 Computers in Chemistry. Course Material for Spring 2002. Introduction to computers, operation, interfacing, programming, and typical applications in chemistry. Applications include data analysis, numerical methods, curve-fitting, chemical modeling, the use of chemical databases, and chemistry on the Internet and the Web. Three class meetings and one laboratory. Prerequisites: Chemistry 2 or 12. Spring 2002. Kounaves

144 Spectroscopic Methods of Analysis. Spectroscopic analytical techniques, including principles and applications of spectroscopic measurements, fundamental interaction of radiation and matter, emission spectroscopy, atomic absorption, UV-visible fluorescence, Fourier transform IR, X-ray techniques, mass spectroscopy, and surface techniques such as AES, ESCA, and SIMS. Three lectures. Prerequisites: Chemistry 42 or 141, or consent. Fall 2001. Robbat

145 Separation Science. Basic separation theory, practice, and instrumentation in gas, liquid, and other chromatographies, membrane and affinity separations, extraction techniques, electrophoresis, and separations based on phase equilibria. Three lectures. Prerequisites: Chemistry 42 or 141, or consent. Robbat

146 Electroanalytical Chemistry. Course Material for Spring 2002 Basic theory and application of modern electrochemical methods of analysis including amperometry, voltammetry, modern cyclic and pulse techniques, and stripping analysis. Mechanisms, kinetics, and electron transfer theory are also covered. Three lectures. Prerequisites: Chemistry 42 or 141, or consent. Spring 2002. Kounaves

150 Intermediate Organic Chemistry. Course Material for Fall 2002 Survey of the principles of organic chemistry. Topics include reaction mechanisms, synthesis, and spectroscopic methods of structure determination. Three lectures. Prerequisite: Chemistry 52. Fall. Members of the Department

151 Physical Organic Chemistry. Advanced organic chemistry with emphasis on structure and reaction mechanisms, uses of kinetics and other physical methods, and dynamic interaction between current theoretical concepts and experiment. Three lectures. Prerequisite: Chemistry 52. Spring 2002 and alternate years. Members of the Department

152 Advanced Organic Synthesis. Study of noteworthy syntheses of complex molecules with a view to developing a rationale and methodology for synthesis. Examination of the mechanism and scope of new bond-forming methods and functional group transformations. Three lectures. Prerequisite: Chemistry 52. Spring 2001 and alternate years. Members of the Department

155 Organic Spectroscopy. Applications of NMR, IR, UV, and mass spectrometry to the identification of organic compounds. Three class meetings. Prerequisite: Chemistry 52. Stolow

157 Medicinal Chemistry. Molecular-level mechanism of action of compounds useful in human medicine. Introduces the biochemistry of a biological system relevant to a particular disease process, then focuses on the detailed interaction of chemotherapeutic agents with the system. Material is drawn principally from the primary literature. Course is not comprehensive. Topics may include antiviral/antitumor agents, compounds affecting immunity and inflammation, antibiotics, nucleic-acid-based therapeutics, and combinatorial drug discovery methods. Prerequisites: Biology 13 and Chemistry 52. Fall 2001 and alternate years. d'Alarcao

161 Advanced Inorganic Chemistry. Atomic and molecular structure. Symmetry operations and symmetry point groups. Chemical bonding in inorganic and coordination compounds. Types of inorganic reactions and their mechanisms. Reactivity of major classes of inorganic compounds. Descriptive chemistry of selected main-group elements. More rigorous than Chemistry 61. May receive credit for only one of Chemistry 61 or 161. Prerequisites: Chemistry 32 and 52. Fall. Members of the Department

162 Chemistry of Transition Elements. Descriptive and theoretical chemistry of transition elements; structure, bonding, reactivity, and spectroscopic properties of metal complexes. Prerequisite: Chemistry 61 or 161. Spring 2001 and alternate years. Members of the Department

163 Diffraction Methods of Structure Determination. Introduction to structure determination methods that give detailed information on atomic arrangements in crystalline solids. Emphasis on single-crystal X-ray diffraction, with some attention to neutron diffraction, and powder methods. Space group symmetry, structure factors, methods of structure solution, and measures of structure accuracy. Prerequisite: consent. Members of the Department

164 Bioinorganic Chemistry. The role of metal ions in living organisms; understanding and modeling. Metal ion transport and storage, biocoordination chemistry of ion pumps. Metal ion folding and cross-linking of biomolecules. Small molecule (oxygen, nitrogen) binding and activation. Hydrolytic and redox metalloenzymes. Structure-function relationships in metalloenzyme mimics. Bioinorganic chemistry and drug design. Prerequisite: Chemistry 61 or 161, or consent. Fall 2000 and alternate years. Rybak-Akimova

165 Physical Methods in Inorganic Chemistry. Spectroscopic methods in inorganic and coordination chemistry: UV-Vis, infrared, Raman, electron paramagnetic resonance, nuclear quadrupole resonance, Mossbauer spectroscopy. Multinuclear NMR, NMR of paramagnetic compounds. Magnetism applications of different methods to electronic structure determination and to studies on complexation in solution. X-ray crystallography. Prerequisite: Chemistry 61 or 161, or consent. Members of the Department

170 Scientific Writing. A writing laboratory based on scientific material encountered in current chemical research, with a focus on the writing and preparation of scientific manuscripts. One-half course. Prerequisite: consent. Fall. Illinger

171 Biochemistry I. First course in a two-course sequence. Chemistry of biological molecules: proteins, lipids, carbohydrates, nucleic acids, etc. Mechanisms of enzyme and ribozyme catalysis. Metabolic pathways, integrated metabolic systems, and molecular physiology. Co-listed as BIO 171. One course. Prerequisites: BIO 13, CHEM 52. Fall. Members of the faculty of the Chemistry and Biology Departments.

172 Biochemistry II. Continuation of CHEM 171. Co-listed as BIO 172. One course. Prerequisites: CHEM 171. Spring. Members of the faculty of the Chemistry and Biology Departments.

191, 192 Seminar in Chemistry. Discussion of specialized problems and current chemical research. Prerequisite: open to qualified advanced students in chemistry. Credit as arranged. Members of the Department

193, 194 Special Topics. Guided individual study of an approved topic. Credit as arranged. Members of the Department

Courses for Graduate Students Only

237, 238 Special Topics in Physical Chemistry. Selected topics of contemporary interest in physical chemistry. Three lectures. Prerequisite: consent. Two courses. Members of the Department.

247, 248 Special Topics in Analytical Chemistry. Selected topics of contemporary interest in analytical and instrumental chemistry. Three lectures. Prerequisite: consent. Two courses. Members of the Department.

257,258 Special Topics in Organic Chemistry. Selected topics of contemporary interest in organic chemistry. Three lectures. Prerequisite: consent. Two courses. Members of the Department.

267, 268 Special Topics in Inorganic Chemistry. Selected topics of contemporary interest in inorganic chemistry. Three lectures. Prerequisite: consent. Two courses. Members of the Department.

293, 294 Special Topics. Guided individual study of an approved topic. Credit as arranged. Members of the Department.

295, 296 Thesis. Guided research on a topic that has been approved as a suitable subject for a master's thesis. Credit as arranged. Members of the Department.

297, 298 Graduate Research. Guided research on a topic suitable for a doctoral dissertation. Credit as arranged. Members of the Department.

401PT Master's Continuation, Part-time.

402FT Master's Continuation, Full-time.

501PT Doctoral Continuation, Part-time.

502FT Doctoral Continuation, Full-time.